Gallus gallus      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 14 genes.  Reviewed (0 or Unreviewed (14

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Gaga-0173
ENSGALG00000040308.2
2
LLPS-Gaga-0856
ENSGALG00000015611.7
E1BZQ5
3
LLPS-Gaga-2036
ENSGALG00000006806.6
4
LLPS-Gaga-2127
ENSGALG00000005618.6
E1C9K0
5
LLPS-Gaga-3703
ENSGALG00000014643.6
H9L0N1
6
LLPS-Gaga-2763
ENSGALG00000010783.4
F1NMN0
CPSF2
7
LLPS-Gaga-0671
ENSGALG00000016424.6
F1NKW5
CPSF3
8
LLPS-Gaga-1837
ENSGALG00000004714.6
E1BV31
CPSF4
9
LLPS-Gaga-2071
ENSGALG00000001817.6
A0A1D5PYS0
CTCFL
10
LLPS-Gaga-1402
ENSGALG00000001504.7
F1P5C0
DDX20
11
LLPS-Gaga-3099
ENSGALG00000013943.6
A0A1D5PZ61
FIP1L1
12
LLPS-Gaga-0240
ENSGALG00000033447.3
P02272
H2AFV
13
LLPS-Gaga-0772
ENSGALG00000002127.6
E1BY33
LSM10
14
LLPS-Gaga-0814
ENSGALG00000038954.2
A0A1D5NYV1
LSM11