Gaeumannomyces graminis      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Gag-0332
GGTG_00372
J3NGI2
20340830
2
LLPS-Gag-0361
GGTG_00835
J3NHU9
20341293
3
LLPS-Gag-1603
GGTG_04619
J3NTL9
20345077
4
LLPS-Gag-0403
GGTG_05894
J3NX87
20346352
5
LLPS-Gag-0384
GGTG_07572
J3P224
20348030
6
LLPS-Gag-0480
GGTG_09466
J3P7H5
20349924
7
LLPS-Gag-1140
GGTG_10313
J3P9Y9
20350771