Dothistroma septosporum      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Dos-0971
DOTSEDRAFT_130763
N1PLA7
DOTSEDRAFT_130763
2
LLPS-Dos-0686
DOTSEDRAFT_133466
N1PHB6
DOTSEDRAFT_133466
3
LLPS-Dos-1149
DOTSEDRAFT_146416
N1PZK2
DOTSEDRAFT_146416
4
LLPS-Dos-0090
DOTSEDRAFT_153030
M2YLW3
DOTSEDRAFT_153030
5
LLPS-Dos-0878
DOTSEDRAFT_67585
N1Q014
DOTSEDRAFT_67585
6
LLPS-Dos-0879
DOTSEDRAFT_72696
M2YN53
DOTSEDRAFT_72696
7
LLPS-Dos-0401
DOTSEDRAFT_79774
N1PL90
DOTSEDRAFT_79774