Chlorocebus sabaeus      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 18 genes.  Reviewed (0 or Unreviewed (18

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Chs-1578
ENSCSAG00000002275.1
A0A0D9S4I1
BAHCC1
2
LLPS-Chs-2234
ENSCSAG00000017276.1
A0A0D9RXH1
CASP8AP2
3
LLPS-Chs-0349
ENSCSAG00000008502.1
A0A0D9R822
CPSF1
4
LLPS-Chs-3445
ENSCSAG00000011300.1
A0A0D9RFW7
CPSF2
5
LLPS-Chs-1125
ENSCSAG00000007125.1
A0A0D9R461
CPSF3
6
LLPS-Chs-3848
ENSCSAG00000017795.1
A0A0D9RYX9
CPSF4
7
LLPS-Chs-2050
ENSCSAG00000003911.1
A0A0D9QV86
CTCF
8
LLPS-Chs-0725
ENSCSAG00000004587.1
A0A0D9QX26
CTR9
9
LLPS-Chs-1089
ENSCSAG00000001582.1
A0A0D9S6F5
DDX20
10
LLPS-Chs-2001
ENSCSAG00000004975.1
A0A0D9QY57
FIP1L1
11
LLPS-Chs-1430
ENSCSAG00000002060.1
A0A0D9S555
GON4L
12
LLPS-Chs-1274
ENSCSAG00000015697.1
A0A0D9RT40
H2AFV
13
LLPS-Chs-2163
ENSCSAG00000002522.1
A0A0D9S3T3
HINFP
14
LLPS-Chs-2645
ENSCSAG00000000134.1
A0A0D9SAG9
LSM10
15
LLPS-Chs-4195
ENSCSAG00000010556.1
A0A0D9RDT8
LSM11
16
LLPS-Chs-1556
ENSCSAG00000002976.1
A0A0D9S2H3
NPAT
17
LLPS-Chs-0835
ENSCSAG00000003115.1
A0A0D9S238
SYMPK
18
LLPS-Chs-3109
ENSCSAG00000011345.1
A0A0D9RG12
TP53