Aspergillus niger      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Asni-0539
An01g05350
A2Q8S1
An01g05350
2
LLPS-Asni-0291
An01g10140
A2QA44
An01g10140
3
LLPS-Asni-0883
An11g00560
A5ABJ1
An11g00560
4
LLPS-Asni-1278
An16g03340
A2R7F5
An16g03340
5
LLPS-Asni-0774
An17g02040
A2R9N2
An17g02040
6
LLPS-Asni-1255
An16g09140
A2R919
cft1
7
LLPS-Asni-0510
An16g01810
A2R702
HTZ1