Arabidopsis thaliana      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 5 genes.  Reviewed (1 or Unreviewed (4

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Art-0925
AT2G38810
Q9SII0
At2g38810
2
LLPS-Art-2675
AT5G23880
Q9LKF9
CPSF100
3
LLPS-Art-2065
AT5G51660
Q9FGR0
CPSF160
4
LLPS-Art-2314
AT1G61010
Q9C952
CPSF73-I
5
LLPS-Art-2399
AT5G01400
Q9M033
ENHANCED SILENCING PHENOTYPE 4