Anolis carolinensis      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 18 genes.  Reviewed (0 or Unreviewed (18

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Anc-1079
ENSACAG00000003306.2
H9G7B4
2
LLPS-Anc-0156
ENSACAG00000015255.3
G1KQX4
BAHCC1
3
LLPS-Anc-0894
ENSACAG00000014391.3
G1KPT9
CASP8AP2
4
LLPS-Anc-0152
ENSACAG00000009655.3
H9GFJ4
CPSF1
5
LLPS-Anc-1013
ENSACAG00000009245.3
G1KIP5
CPSF2
6
LLPS-Anc-2548
ENSACAG00000001759.3
G1KA18
CPSF3
7
LLPS-Anc-2039
ENSACAG00000012941.3
H9GJF7
CPSF4
8
LLPS-Anc-3375
ENSACAG00000001050.3
H9G4Q0
CTCF
9
LLPS-Anc-0158
ENSACAG00000008611.3
G1KI41
CTR9
10
LLPS-Anc-0007
ENSACAG00000006235.3
G1KF87
DDX20
11
LLPS-Anc-2292
ENSACAG00000010556.3
G1KKA4
fip1l1
12
LLPS-Anc-1549
ENSACAG00000003005.3
H9G779
gon4l
13
LLPS-Anc-1174
ENSACAG00000006025.3
H9GAV4
H2AFV
14
LLPS-Anc-1508
ENSACAG00000002495.3
H9G6A9
HINFP
15
LLPS-Anc-1449
ENSACAG00000022533.2
H9GVA1
LOC103282543
16
LLPS-Anc-1923
ENSACAG00000001231.2
H9G4T7
LSM10
17
LLPS-Anc-0110
ENSACAG00000006020.3
H9GAV0
NPAT
18
LLPS-Anc-1154
ENSACAG00000004126.3
H9G8S2
SYMPK