Amborella trichopoda      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Amt-0403
AMTR_s00007p00145770
W1PBI3
AMTR_s00007p00145770
2
LLPS-Amt-0985
AMTR_s00009p00247750
W1NGX2
AMTR_s00009p00247750
3
LLPS-Amt-1370
AMTR_s00011p00266610
W1NH44
AMTR_s00011p00266610
4
LLPS-Amt-2030
AMTR_s00024p00227830
W1PU76
AMTR_s00024p00227830
5
LLPS-Amt-0995
AMTR_s00033p00031310
U5CW59
AMTR_s00033p00031310
6
LLPS-Amt-0174
AMTR_s00041p00037520
W1PZ33
AMTR_s00041p00037520