Poecilia formosa      Gemini of cajal body


※ Gemini of cajal body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Gemini of Cajal bodies, also called as Gemini of coiled bodies or nuclear gems, is a kind of these bodies located in Nucleus of spherical shape, It do not contain snRNPs. The function of nuclear gems is still unknown, may be related to further maturation, storage or recycling of splicing factors (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 11 genes.  Reviewed (0 or Unreviewed (11

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Pof-0026
ENSPFOG00000009309.2
A0A087XU04
2
LLPS-Pof-1048
ENSPFOG00000016671.1
A0A087YFF0
3
LLPS-Pof-1433
ENSPFOG00000014660.2
A0A087Y9K6
4
LLPS-Pof-1451
ENSPFOG00000010540.2
A0A087XXS3
5
LLPS-Pof-1673
ENSPFOG00000007786.1
A0A087XPU2
6
LLPS-Pof-1792
ENSPFOG00000008882.1
A0A087XSR6
7
LLPS-Pof-1960
ENSPFOG00000008873.2
A0A087XSV1
8
LLPS-Pof-2045
ENSPFOG00000011252.2
A0A087XZM2
9
LLPS-Pof-3146
ENSPFOG00000016117.2
A0A087YDR7
10
LLPS-Pof-3574
ENSPFOG00000004081.2
A0A087XDU3
11
LLPS-Pof-2679
ENSPFOG00000011964.2
A0A096LUI4
GEMIN5 (1 of many)