Bos taurus      Gemini of cajal body


※ Gemini of cajal body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Gemini of Cajal bodies, also called as Gemini of coiled bodies or nuclear gems, is a kind of these bodies located in Nucleus of spherical shape, It do not contain snRNPs. The function of nuclear gems is still unknown, may be related to further maturation, storage or recycling of splicing factors (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 11 genes.  Reviewed (1 or Unreviewed (10

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Bot-0077
ENSBTAG00000005757.6
Q28009
FUS
2
LLPS-Bot-2030
ENSBTAG00000018717.6
F1MRW7
DDX20
3
LLPS-Bot-4289
ENSBTAG00000020930.5
E1BEK3
GEMIN2
4
LLPS-Bot-2256
ENSBTAG00000013393.6
F1MAW0
GEMIN4
5
LLPS-Bot-3992
ENSBTAG00000012095.6
E1BJG3
GEMIN5
6
LLPS-Bot-1544
ENSBTAG00000015521.4
Q2KHW8
GEMIN6
7
LLPS-Bot-0857
ENSBTAG00000010668.4
Q17QA0
GEMIN7
8
LLPS-Bot-4195
ENSBTAG00000010289.5
Q1LZ79
GEMIN8
9
LLPS-Bot-0604
ENSBTAG00000048800.1
Q1RMR2
SNRNP70
10
LLPS-Bot-0481
ENSBTAG00000014175.6
Q5E959
STRAP
11
LLPS-Bot-0302
ENSBTAG00000003697.6
G3MX91
TARDBP