Anas platyrhynchos      Gemini of cajal body


※ Gemini of cajal body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Gemini of Cajal bodies, also called as Gemini of coiled bodies or nuclear gems, is a kind of these bodies located in Nucleus of spherical shape, It do not contain snRNPs. The function of nuclear gems is still unknown, may be related to further maturation, storage or recycling of splicing factors (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Anp-0009
ENSAPLG00000013826.1
U3J2D1
DDX20
2
LLPS-Anp-2057
ENSAPLG00000012052.1
U3IX72
GEMIN2
3
LLPS-Anp-0206
ENSAPLG00000006816.1
U3IGT9
GEMIN5
4
LLPS-Anp-0716
ENSAPLG00000012461.1
R0JWL8
GEMIN6
5
LLPS-Anp-0068
ENSAPLG00000013061.1
U3J022
GEMIN8
6
LLPS-Anp-2311
ENSAPLG00000010912.1
U3ITT1
LOC101792326
7
LLPS-Anp-2547
ENSAPLG00000011004.1
U3IU43
STRAP
8
LLPS-Anp-0189
ENSAPLG00000006001.1
U3IED4
TARDBP