Rhinopithecus bieti      DNA damage foci


※ DNA damage foci introduction

    DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a chromosomal DNA double-strand break to form microscopically visible, subnuclear foci called DNA damage foci, also called (ionizing) radiation‐induced foci (IRIF or RIF) or DNA repair foci. The discovery of DNA damage foci has opened a new dimension to the field of DNA damage signaling. Analysis of the spatiotemporal dynamics of DSB induction and repair in situ or even in live cells has now become a standard method in many different fields (1).

Reference
1. Rothkamm, K., Barnard, S., Moquet, J., Ellender, M., Rana, Z., & Burdak-Rothkamm, S. (2015) DNA damage foci: Meaning and significance. Environ Mol Mutagen, 56(6), 491-504. PMID: 25773265


There are 10 genes.  Reviewed (0 or Unreviewed (10

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Rhb-2981
ENSRBIG00000032024.1
A0A2K6KXB1
2
LLPS-Rhb-3363
ENSRBIG00000033471.1
A0A2K6L676
3
LLPS-Rhb-2627
ENSRBIG00000034107.1
A0A2K6L9Z6
ATM
4
LLPS-Rhb-4103
ENSRBIG00000044219.1
A0A2K6N195
ATMIN
5
LLPS-Rhb-1468
ENSRBIG00000042196.1
A0A2K6MN44
FUS
6
LLPS-Rhb-3106
ENSRBIG00000019317.1
A0A2K6JYN0
H2AFX
7
LLPS-Rhb-3998
ENSRBIG00000031951.1
A0A2K6KWR1
MDC1
8
LLPS-Rhb-0496
ENSRBIG00000030819.1
A0A2K6KQV2
PRKDC
9
LLPS-Rhb-3028
ENSRBIG00000033680.1
A0A2K6L773
RBM45
10
LLPS-Rhb-1114
ENSRBIG00000032272.1
A0A2K6KZ34
TP53BP1