Ovis aries      DNA damage foci


※ DNA damage foci introduction

    DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a chromosomal DNA double-strand break to form microscopically visible, subnuclear foci called DNA damage foci, also called (ionizing) radiation‐induced foci (IRIF or RIF) or DNA repair foci. The discovery of DNA damage foci has opened a new dimension to the field of DNA damage signaling. Analysis of the spatiotemporal dynamics of DSB induction and repair in situ or even in live cells has now become a standard method in many different fields (1).

Reference
1. Rothkamm, K., Barnard, S., Moquet, J., Ellender, M., Rana, Z., & Burdak-Rothkamm, S. (2015) DNA damage foci: Meaning and significance. Environ Mol Mutagen, 56(6), 491-504. PMID: 25773265


There are 12 genes.  Reviewed (0 or Unreviewed (12

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Ova-1188
ENSOARG00000002203.1
W5NVY0
2
LLPS-Ova-3633
ENSOARG00000019117.1
W5QCT5
3
LLPS-Ova-1088
ENSOARG00000011894.1
W5PQN7
ATM
4
LLPS-Ova-1593
ENSOARG00000006192.1
W5P8B0
ATR
5
LLPS-Ova-0772
ENSOARG00000017039.1
W5Q6F0
H2AFX
6
LLPS-Ova-1923
ENSOARG00000020951.1
W5QIG5
HDAC1
7
LLPS-Ova-3628
ENSOARG00000011746.1
W5PQ65
MDC1
8
LLPS-Ova-1488
ENSOARG00000011884.1
W5PQQ8
PRKDC
9
LLPS-Ova-2674
ENSOARG00000015021.1
W5Q081
RAD50
10
LLPS-Ova-0042
ENSOARG00000020254.1
W5QG99
RAD51
11
LLPS-Ova-3849
ENSOARG00000017348.1
W5Q7D2
RBM45
12
LLPS-Ova-1973
ENSOARG00000010147.1
W5PKC0
TP53BP1