Macaca fascicularis      DNA damage foci


※ DNA damage foci introduction

    DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a chromosomal DNA double-strand break to form microscopically visible, subnuclear foci called DNA damage foci, also called (ionizing) radiation‐induced foci (IRIF or RIF) or DNA repair foci. The discovery of DNA damage foci has opened a new dimension to the field of DNA damage signaling. Analysis of the spatiotemporal dynamics of DSB induction and repair in situ or even in live cells has now become a standard method in many different fields (1).

Reference
1. Rothkamm, K., Barnard, S., Moquet, J., Ellender, M., Rana, Z., & Burdak-Rothkamm, S. (2015) DNA damage foci: Meaning and significance. Environ Mol Mutagen, 56(6), 491-504. PMID: 25773265


There are 11 genes.  Reviewed (0 or Unreviewed (11

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Maf-0754
ENSMFAG00000001093.1
2
LLPS-Maf-1117
ENSMFAG00000031794.1
3
LLPS-Maf-3383
ENSMFAG00000034367.1
4
LLPS-Maf-2706
ENSMFAG00000042524.1
G7PKX6
EGM_04104
5
LLPS-Maf-0037
ENSMFAG00000004053.1
G7PNR0
EGM_06194
6
LLPS-Maf-3977
ENSMFAG00000001151.1
G7P010
EGM_11028
7
LLPS-Maf-4284
ENSMFAG00000034228.1
G7P885
EGM_15366
8
LLPS-Maf-1412
ENSMFAG00000044559.1
G7PAX4
EGM_15862
9
LLPS-Maf-3999
ENSMFAG00000002945.1
G7PB71
EGM_15917
10
LLPS-Maf-1056
ENSMFAG00000033291.1
G7PBS9
EGM_17298
11
LLPS-Maf-3852
ENSMFAG00000009238.1
G7PPA0
H2AFX