Gasterosteus aculeatus      DNA damage foci


※ DNA damage foci introduction

    DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a chromosomal DNA double-strand break to form microscopically visible, subnuclear foci called DNA damage foci, also called (ionizing) radiation‐induced foci (IRIF or RIF) or DNA repair foci. The discovery of DNA damage foci has opened a new dimension to the field of DNA damage signaling. Analysis of the spatiotemporal dynamics of DSB induction and repair in situ or even in live cells has now become a standard method in many different fields (1).

Reference
1. Rothkamm, K., Barnard, S., Moquet, J., Ellender, M., Rana, Z., & Burdak-Rothkamm, S. (2015) DNA damage foci: Meaning and significance. Environ Mol Mutagen, 56(6), 491-504. PMID: 25773265


There are 9 genes.  Reviewed (0 or Unreviewed (9

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Gaa-0314
ENSGACG00000010787.1
G3P9P8
2
LLPS-Gaa-0566
ENSGACG00000001974.2
G3NB89
3
LLPS-Gaa-1456
ENSGACG00000006981.2
G3NV93
4
LLPS-Gaa-1567
ENSGACG00000012241.1
G3PF23
5
LLPS-Gaa-1870
ENSGACG00000011659.1
G3PCX6
6
LLPS-Gaa-3003
ENSGACG00000015975.1
G3PTZ2
7
LLPS-Gaa-3550
ENSGACG00000020414.1
G3QAS2
8
LLPS-Gaa-3631
ENSGACG00000020717.1
G3QBX6
9
LLPS-Gaa-2945
ENSGACG00000017453.1
G3PZM4
TP53BP1