Arabidopsis thaliana      DNA damage foci


※ DNA damage foci introduction

    DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a chromosomal DNA double-strand break to form microscopically visible, subnuclear foci called DNA damage foci, also called (ionizing) radiation‐induced foci (IRIF or RIF) or DNA repair foci. The discovery of DNA damage foci has opened a new dimension to the field of DNA damage signaling. Analysis of the spatiotemporal dynamics of DSB induction and repair in situ or even in live cells has now become a standard method in many different fields (1).

Reference
1. Rothkamm, K., Barnard, S., Moquet, J., Ellender, M., Rana, Z., & Burdak-Rothkamm, S. (2015) DNA damage foci: Meaning and significance. Environ Mol Mutagen, 56(6), 491-504. PMID: 25773265


There are 5 genes.  Reviewed (1 or Unreviewed (4

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Art-1543
AT4G38130
O22446
HDA19
2
LLPS-Art-2717
AT3G48190
Q9M3G7
ATM
3
LLPS-Art-2992
AT5G40820
Q9FKS4
ATR
4
LLPS-Art-1978
AT5G66730
Q9LVQ7
ENY
5
LLPS-Art-2234
AT5G20850
P94102
RAD51