Ursus maritimus      Chromatoid body


※ Chromatoid body introduction

    A single large granule of nuage, presents in post-meiotic spermatids is called the chromatoid body (1). Multiple proteins and some mRNAs have been found to localized to the chromatoid body including mouse VASA homolog , tudor-domain containing 1 (TDRD1), tudor-domain containing 6 (TDRD6), and tudor-domain containing 7 (TDRD7) , transition protein 2 (Tnp2), RANBP9, as a known MVH interactor also localizes to it. Its formation is related to the coalescence of intermitochondrial cement granules. In fact, the formation of the chromatoid body is not required for microRNA biogenesis, but might be important for its action on target mRNAs (1). In mice, the chromatoid body is a structure resembles Gp, TDRD6 plays a role in establishing the body and the localization of piRNA pathway components to this body (2).

Reference
1. Woodruff, J. B., Hyman, A. A., & Boke, E. (2018) Organization and Function of Non-dynamic Biomolecular Condensates. Trends Biochem Sci, 43(2), 81-94. PMID: 30086300
2. Ma, L., Buchold, G. M., Greenbaum, M. P., Roy, A., Burns, K. H., Zhu, H., et al. (2009) GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet, 5(9), e1000635. PMID: 19730684


There are 97 genes.  Reviewed (0 or Unreviewed (97

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Urm-0174
ENSUMAG00000024131.1
2
LLPS-Urm-2300
ENSUMAG00000009594.1
3
LLPS-Urm-3771
ENSUMAG00000004507.1
A0A384BZU6
ADAD1
4
LLPS-Urm-0166
ENSUMAG00000015841.1
A0A384C0S3
ADAD2
5
LLPS-Urm-1030
ENSUMAG00000000898.1
A0A384BRS9
AFAP1L2
6
LLPS-Urm-4072
ENSUMAG00000004542.1
A0A384CG35
AKAP4
7
LLPS-Urm-3825
ENSUMAG00000002973.1
A0A384DB80
ASZ1
8
LLPS-Urm-2105
ENSUMAG00000017697.1
A0A384BYH6
CASC3
9
LLPS-Urm-1700
ENSUMAG00000003979.1
A0A384C822
CD74
10
LLPS-Urm-0220
ENSUMAG00000006924.1
A0A384BPS4
CENPV
11
LLPS-Urm-0275
ENSUMAG00000015120.1
A0A384CMH9
CNBP
12
LLPS-Urm-2682
ENSUMAG00000000016.1
Q8SJH3
COX1
13
LLPS-Urm-3636
ENSUMAG00000021775.1
A0A384D932
CTSB
14
LLPS-Urm-1945
ENSUMAG00000020222.1
A0A384D485
DCP1A
15
LLPS-Urm-1826
ENSUMAG00000023450.1
A0A384CV08
DDX1
16
LLPS-Urm-3063
ENSUMAG00000001803.1
A0A384BVB5
DDX25
17
LLPS-Urm-1264
ENSUMAG00000009291.1
A0A384C423
DDX4
18
LLPS-Urm-0935
ENSUMAG00000017787.1
A0A384CAG4
DDX5
19
LLPS-Urm-0087
ENSUMAG00000016482.1
A0A384CX23
DHX9
20
LLPS-Urm-1544
ENSUMAG00000003027.1
A0A384CNA8
DICER1
21
LLPS-Urm-2500
ENSUMAG00000019571.1
A0A384D1M8
EDC4
22
LLPS-Urm-0373
ENSUMAG00000012312.1
A0A384BKG6
EEF1A1
23
LLPS-Urm-0913
ENSUMAG00000014617.1
A0A384CB24
EIF4A3
24
LLPS-Urm-0076
ENSUMAG00000004901.1
A0A384DF44
EIF4E
25
LLPS-Urm-2770
ENSUMAG00000014798.1
A0A384DRZ2
ELAVL1
26
LLPS-Urm-0210
ENSUMAG00000002829.1
A0A384BKV2
ENO4
27
LLPS-Urm-0139
ENSUMAG00000016019.1
A0A384BRQ6
EWSR1
28
LLPS-Urm-1365
ENSUMAG00000015007.1
A0A384BXJ7
FABP9
29
LLPS-Urm-0586
ENSUMAG00000004675.1
A0A384D6J4
FYCO1
30
LLPS-Urm-0309
ENSUMAG00000001699.1
A0A384BPW4
HNRNPA2B1
31
LLPS-Urm-2529
ENSUMAG00000016485.1
A0A384CI07
HNRNPF
32
LLPS-Urm-2473
ENSUMAG00000014575.1
A0A384DRY1
HNRNPM
33
LLPS-Urm-0751
ENSUMAG00000012322.1
A0A384CL04
HNRNPU
34
LLPS-Urm-1322
ENSUMAG00000002491.1
A0A384BJG3
HSP90AA1
35
LLPS-Urm-1065
ENSUMAG00000005339.1
A0A384C5B5
HSP90AB1
36
LLPS-Urm-1756
ENSUMAG00000013422.1
A0A384DTJ4
HSPA1A
37
LLPS-Urm-0897
ENSUMAG00000013467.1
A0A384CWF6
HSPA2
38
LLPS-Urm-1667
ENSUMAG00000000428.1
A0A384BR37
IGF2BP3
39
LLPS-Urm-0401
ENSUMAG00000025049.1
A0A384DHP3
ILF3
40
LLPS-Urm-1412
ENSUMAG00000022211.1
A0A384D4K3
IP6K1
41
LLPS-Urm-1465
ENSUMAG00000008568.1
A0A384CE72
KHDRBS1
42
LLPS-Urm-3308
ENSUMAG00000020905.1
A0A384BKN4
LAMP1
43
LLPS-Urm-0009
ENSUMAG00000020515.1
A0A384BRD8
LDHA
44
LLPS-Urm-1078
ENSUMAG00000001559.1
A0A384BPV9
LOC103658902
45
LLPS-Urm-1113
ENSUMAG00000020562.1
A0A384C9T6
LOC103665033
46
LLPS-Urm-1031
ENSUMAG00000020861.1
A0A384C8G5
LOC103665043
47
LLPS-Urm-0460
ENSUMAG00000020991.1
A0A384CA24
LOC103665197
48
LLPS-Urm-2172
ENSUMAG00000004268.1
A0A384CLU5
LOC103669237
49
LLPS-Urm-1433
ENSUMAG00000001131.1
A0A384DE05
LOC103677773
50
LLPS-Urm-1256
ENSUMAG00000002357.1
A0A384DKF1
LOC103679777
51
LLPS-Urm-0101
ENSUMAG00000000338.1
A0A384BN22
LYAR
52
LLPS-Urm-1859
ENSUMAG00000016528.1
A0A384CFX9
MAEL
53
LLPS-Urm-2631
ENSUMAG00000016134.1
A0A384CLF9
MAGOHB
54
LLPS-Urm-1344
ENSUMAG00000015789.1
A0A384C160
NCL
55
LLPS-Urm-0863
ENSUMAG00000004163.1
A0A384BUM9
NEDD1
56
LLPS-Urm-3173
ENSUMAG00000019739.1
A0A384BZ62
ODF1
57
LLPS-Urm-2358
ENSUMAG00000017554.1
A0A384BXX2
PABPC1
58
LLPS-Urm-1285
ENSUMAG00000020294.1
A0A384BXX6
PIWIL1
59
LLPS-Urm-0547
ENSUMAG00000005016.1
A0A384CZT3
PIWIL2
60
LLPS-Urm-0262
ENSUMAG00000013839.1
A0A384BP53
PMPCB
61
LLPS-Urm-0601
ENSUMAG00000017815.1
A0A384CA26
RANBP9
62
LLPS-Urm-3167
ENSUMAG00000017581.1
A0A384BW18
RANGRF
63
LLPS-Urm-1040
ENSUMAG00000011736.1
A0A384DK02
RBM14
64
LLPS-Urm-1675
ENSUMAG00000010298.1
A0A384DG32
RBM8A
65
LLPS-Urm-2591
ENSUMAG00000013953.1
A0A384C7A2
RNF17
66
LLPS-Urm-0984
ENSUMAG00000013210.1
A0A384CDD7
RPL11
67
LLPS-Urm-1512
ENSUMAG00000011748.1
A0A384CFD2
RPL23A
68
LLPS-Urm-1335
ENSUMAG00000003275.1
A0A384D0I3
RPL24
69
LLPS-Urm-0234
ENSUMAG00000003973.1
A0A384C8C8
RPS14
70
LLPS-Urm-0138
ENSUMAG00000024295.1
A0A384CRT5
RPS8
71
LLPS-Urm-0799
ENSUMAG00000006636.1
A0A384CK10
SMG1
72
LLPS-Urm-2595
ENSUMAG00000009306.1
A0A384CGF4
SMG6
73
LLPS-Urm-1471
ENSUMAG00000016197.1
A0A384DDG1
SPERT
74
LLPS-Urm-1562
ENSUMAG00000000455.1
A0A384CH42
SRSF1
75
LLPS-Urm-3884
ENSUMAG00000009985.1
A0A384C9U4
SRSF3
76
LLPS-Urm-1508
ENSUMAG00000001224.1
A0A384BPU9
STK31
77
LLPS-Urm-0918
ENSUMAG00000000705.1
A0A384BKG1
TDRD1
78
LLPS-Urm-2485
ENSUMAG00000014526.1
A0A384DDA7
TDRD3
79
LLPS-Urm-3022
ENSUMAG00000020642.1
A0A384CKY0
TDRD5
80
LLPS-Urm-0625
ENSUMAG00000005127.1
A0A384C5L0
TDRD6
81
LLPS-Urm-0711
ENSUMAG00000011725.1
A0A384DGW6
TDRD7
82
LLPS-Urm-0550
ENSUMAG00000024822.1
A0A384DBG3
TDRD9
83
LLPS-Urm-1521
ENSUMAG00000002004.1
A0A384CCP4
TEKT2
84
LLPS-Urm-1351
ENSUMAG00000003930.1
A0A384CKK6
TNP2
85
LLPS-Urm-0740
ENSUMAG00000007635.1
A0A384C3W9
TNPO1
86
LLPS-Urm-0827
ENSUMAG00000008274.1
A0A384CLL8
TNRC6A
87
LLPS-Urm-3162
ENSUMAG00000025434.1
A0A384CNP6
TOMM34
88
LLPS-Urm-2120
ENSUMAG00000004912.1
A0A384D8R6
TRA2B
89
LLPS-Urm-0921
ENSUMAG00000012992.1
A0A384BT08
TTC21B
90
LLPS-Urm-2572
ENSUMAG00000022418.1
A0A384D1Z9
UBTD1
91
LLPS-Urm-0405
ENSUMAG00000006652.1
A0A384D5N5
UPF1
92
LLPS-Urm-0238
ENSUMAG00000017495.1
A0A384DIQ7
USP9X
93
LLPS-Urm-0341
ENSUMAG00000012639.1
A0A384C7E5
VIM
94
LLPS-Urm-3644
ENSUMAG00000007756.1
A0A384CI75
VPS26A
95
LLPS-Urm-3922
ENSUMAG00000007502.1
A0A384D2D4
VPS35
96
LLPS-Urm-4061
ENSUMAG00000015222.1
A0A384BUQ4
YBX2
97
LLPS-Urm-0028
ENSUMAG00000023877.1
A0A384DLR2
YTHDC2