Ovis aries      Chromatoid body


※ Chromatoid body introduction

    A single large granule of nuage, presents in post-meiotic spermatids is called the chromatoid body (1). Multiple proteins and some mRNAs have been found to localized to the chromatoid body including mouse VASA homolog , tudor-domain containing 1 (TDRD1), tudor-domain containing 6 (TDRD6), and tudor-domain containing 7 (TDRD7) , transition protein 2 (Tnp2), RANBP9, as a known MVH interactor also localizes to it. Its formation is related to the coalescence of intermitochondrial cement granules. In fact, the formation of the chromatoid body is not required for microRNA biogenesis, but might be important for its action on target mRNAs (1). In mice, the chromatoid body is a structure resembles Gp, TDRD6 plays a role in establishing the body and the localization of piRNA pathway components to this body (2).

Reference
1. Woodruff, J. B., Hyman, A. A., & Boke, E. (2018) Organization and Function of Non-dynamic Biomolecular Condensates. Trends Biochem Sci, 43(2), 81-94. PMID: 30086300
2. Ma, L., Buchold, G. M., Greenbaum, M. P., Roy, A., Burns, K. H., Zhu, H., et al. (2009) GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet, 5(9), e1000635. PMID: 19730684


There are 99 genes.  Reviewed (0 or Unreviewed (99

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Ova-0036
ENSOARG00000020087.1
W5QFR8
2
LLPS-Ova-0783
ENSOARG00000011060.1
W5PN31
3
LLPS-Ova-2058
ENSOARG00000020053.1
W5QFN3
4
LLPS-Ova-2315
ENSOARG00000002880.1
W5NY16
5
LLPS-Ova-2832
ENSOARG00000017009.1
W5Q6B9
6
LLPS-Ova-3450
ENSOARG00000014989.1
W5Q039
7
LLPS-Ova-2692
ENSOARG00000014762.1
W5PZE9
AFAP1L2
8
LLPS-Ova-3560
ENSOARG00000003763.1
W5P0S5
AGO2
9
LLPS-Ova-1233
ENSOARG00000010039.1
W5PJZ7
AKAP4
10
LLPS-Ova-2139
ENSOARG00000018979.1
W5QCD4
ASZ1
11
LLPS-Ova-1428
ENSOARG00000013239.1
W5PUQ8
CASC3
12
LLPS-Ova-1924
ENSOARG00000007229.1
W5PBE0
CD74
13
LLPS-Ova-0955
ENSOARG00000003577.1
W5P067
CNBP
14
LLPS-Ova-3601
ENSOARG00000015263.1
P83205
CTSB
15
LLPS-Ova-1054
ENSOARG00000016637.1
W5Q580
DCP1A
16
LLPS-Ova-0451
ENSOARG00000016369.1
W5Q4E3
DDX1
17
LLPS-Ova-0179
ENSOARG00000011935.1
W5PQR9
DDX25
18
LLPS-Ova-0755
ENSOARG00000007644.1
W5PCP3
DDX4
19
LLPS-Ova-0444
ENSOARG00000019089.1
W5QCQ4
DHX9
20
LLPS-Ova-0806
ENSOARG00000015465.1
W5Q1K4
DICER1
21
LLPS-Ova-2464
ENSOARG00000003220.1
W5NZ39
EDC4
22
LLPS-Ova-0374
ENSOARG00000014476.1
W5PYK0
EIF4A1
23
LLPS-Ova-0561
ENSOARG00000002169.1
W5NVU4
EIF4A3
24
LLPS-Ova-1033
ENSOARG00000015905.1
W5Q2Y9
EIF4E
25
LLPS-Ova-2511
ENSOARG00000003168.1
W5NYX6
ELAVL1
26
LLPS-Ova-4154
ENSOARG00000017691.1
W5Q8E7
ENO4
27
LLPS-Ova-2888
ENSOARG00000003642.1
W5P0E1
EWSR1
28
LLPS-Ova-2187
ENSOARG00000009210.1
W5PHH0
FABP9
29
LLPS-Ova-4135
ENSOARG00000009139.1
W5PH99
FYCO1
30
LLPS-Ova-2612
ENSOARG00000010132.1
W5PK95
HNRNPA2B1
31
LLPS-Ova-2406
ENSOARG00000017442.1
W5Q7M7
HNRNPA3
32
LLPS-Ova-0022
ENSOARG00000000824.1
W5NRR0
HNRNPDL
33
LLPS-Ova-0526
ENSOARG00000003995.1
W5P1G7
HNRNPF
34
LLPS-Ova-2363
ENSOARG00000003368.1
W5NZJ3
HNRNPH1
35
LLPS-Ova-0778
ENSOARG00000003961.1
W5P1D7
HNRNPM
36
LLPS-Ova-1103
ENSOARG00000004985.1
W5P4I9
HNRNPU
37
LLPS-Ova-0115
ENSOARG00000009343.1
W5PHW0
HSP90AB1
38
LLPS-Ova-0060
ENSOARG00000008800.1
W5PG95
HSPA1A
39
LLPS-Ova-0858
ENSOARG00000001015.1
W5NSB0
HSPA2
40
LLPS-Ova-1133
ENSOARG00000003903.1
A8DR93
HSPCA
41
LLPS-Ova-0335
ENSOARG00000016982.1
W5Q697
ILF3
42
LLPS-Ova-3203
ENSOARG00000012413.1
W5PS73
IP6K1
43
LLPS-Ova-0962
ENSOARG00000000666.1
W5NR95
KHDRBS1
44
LLPS-Ova-0970
ENSOARG00000008215.1
W5PEE9
LAMP1
45
LLPS-Ova-3338
ENSOARG00000009602.1
W5PIN4
LDHA
46
LLPS-Ova-3222
ENSOARG00000020089.1
W5QFS2
LOC101115410
47
LLPS-Ova-1285
ENSOARG00000000856.1
W5QJA7
LOC101118037
48
LLPS-Ova-0168
ENSOARG00000007661.1
W5PCQ4
LYAR
49
LLPS-Ova-1468
ENSOARG00000011888.1
W5PQL8
MAEL
50
LLPS-Ova-0825
ENSOARG00000020936.1
W5QIE6
MAGOHB
51
LLPS-Ova-2685
ENSOARG00000000016.1
O78749
MT-CO1
52
LLPS-Ova-0936
ENSOARG00000020709.1
W5QHQ7
NCL
53
LLPS-Ova-1246
ENSOARG00000012759.1
W5PT89
NEDD1
54
LLPS-Ova-0220
ENSOARG00000017172.1
W5Q6T4
ODF1
55
LLPS-Ova-2449
ENSOARG00000000095.1
W5NPI6
PABPC1
56
LLPS-Ova-0731
ENSOARG00000019516.1
W5QE14
PCBP1
57
LLPS-Ova-0402
ENSOARG00000016466.1
W5Q4P4
PCBP2
58
LLPS-Ova-2534
ENSOARG00000016263.1
W5Q433
PIWIL1
59
LLPS-Ova-0287
ENSOARG00000010357.1
W5PKY5
PIWIL2
60
LLPS-Ova-3332
ENSOARG00000018965.1
W5QCC2
PMPCB
61
LLPS-Ova-4427
ENSOARG00000014002.1
W5PX46
PSIP1
62
LLPS-Ova-1158
ENSOARG00000013253.1
W5PUR9
RANBP9
63
LLPS-Ova-1357
ENSOARG00000000523.1
W5NQU3
RANGRF
64
LLPS-Ova-1588
ENSOARG00000007565.1
W5PCF3
RBM14
65
LLPS-Ova-1313
ENSOARG00000020634.1
W5QHH5
RBM8A
66
LLPS-Ova-1861
ENSOARG00000012752.1
W5PT72
RNASE6
67
LLPS-Ova-0607
ENSOARG00000014641.1
W5PZ21
RNF17
68
LLPS-Ova-0961
ENSOARG00000007306.1
W5PBM0
RPL11
69
LLPS-Ova-1548
ENSOARG00000003480.1
D4P8H6
rpl23a
70
LLPS-Ova-1291
ENSOARG00000018519.1
W5QAY7
RPL24
71
LLPS-Ova-1482
ENSOARG00000007328.1
W5PBP1
RPS14
72
LLPS-Ova-0087
ENSOARG00000001136.1
W5NSP2
RPS8
73
LLPS-Ova-2239
ENSOARG00000010928.1
W5PMR0
SMG1
74
LLPS-Ova-1655
ENSOARG00000015076.1
W5Q0E9
SMG6
75
LLPS-Ova-0757
ENSOARG00000007736.1
W5PCY9
SPERT
76
LLPS-Ova-3115
ENSOARG00000008323.1
W5PEQ9
SRSF1
77
LLPS-Ova-3389
ENSOARG00000013584.1
B0FZL9
SRSF3
78
LLPS-Ova-4455
ENSOARG00000011063.1
W5PN39
STK31
79
LLPS-Ova-4349
ENSOARG00000014200.1
W5PXR9
TDRD1
80
LLPS-Ova-0120
ENSOARG00000006244.1
W5P8D4
TDRD3
81
LLPS-Ova-2998
ENSOARG00000017299.1
W5Q779
TDRD5
82
LLPS-Ova-1281
ENSOARG00000010906.1
W5PMM0
TDRD6
83
LLPS-Ova-3073
ENSOARG00000011287.1
W5PNS6
TDRD7
84
LLPS-Ova-1926
ENSOARG00000006675.1
W5P9P8
TDRD9
85
LLPS-Ova-0618
ENSOARG00000019613.1
W5QEB5
TEKT2
86
LLPS-Ova-1732
ENSOARG00000014487.1
W5PYL1
TEKT4
87
LLPS-Ova-0259
ENSOARG00000006554.1
W5P9A8
TNP2
88
LLPS-Ova-0573
ENSOARG00000005038.1
W5P4Q1
TNPO1
89
LLPS-Ova-3268
ENSOARG00000017950.1
W5Q977
TNRC6A
90
LLPS-Ova-2372
ENSOARG00000004587.1
W5P3A8
TOMM34
91
LLPS-Ova-1409
ENSOARG00000015287.1
W5Q119
TOP3B
92
LLPS-Ova-0759
ENSOARG00000020552.1
W5QH84
TRA2B
93
LLPS-Ova-0071
ENSOARG00000005011.1
W5P4N3
TTC21B
94
LLPS-Ova-4077
ENSOARG00000010847.1
W5PMF5
UBTD1
95
LLPS-Ova-1663
ENSOARG00000002046.1
W5NVJ3
USP9X
96
LLPS-Ova-1197
ENSOARG00000011328.1
W5PNW7
VIM
97
LLPS-Ova-1939
ENSOARG00000005337.1
W5P5M8
VPS26A
98
LLPS-Ova-3349
ENSOARG00000015518.1
W5Q1R1
VPS35
99
LLPS-Ova-0416
ENSOARG00000016223.1
W5Q3Z2
YTHDC2