Oryzias latipes      Chromatoid body


※ Chromatoid body introduction

    A single large granule of nuage, presents in post-meiotic spermatids is called the chromatoid body (1). Multiple proteins and some mRNAs have been found to localized to the chromatoid body including mouse VASA homolog , tudor-domain containing 1 (TDRD1), tudor-domain containing 6 (TDRD6), and tudor-domain containing 7 (TDRD7) , transition protein 2 (Tnp2), RANBP9, as a known MVH interactor also localizes to it. Its formation is related to the coalescence of intermitochondrial cement granules. In fact, the formation of the chromatoid body is not required for microRNA biogenesis, but might be important for its action on target mRNAs (1). In mice, the chromatoid body is a structure resembles Gp, TDRD6 plays a role in establishing the body and the localization of piRNA pathway components to this body (2).

Reference
1. Woodruff, J. B., Hyman, A. A., & Boke, E. (2018) Organization and Function of Non-dynamic Biomolecular Condensates. Trends Biochem Sci, 43(2), 81-94. PMID: 30086300
2. Ma, L., Buchold, G. M., Greenbaum, M. P., Roy, A., Burns, K. H., Zhu, H., et al. (2009) GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet, 5(9), e1000635. PMID: 19730684


There are 74 genes.  Reviewed (0 or Unreviewed (74

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Orl-0154
ENSORLG00000015842.2
H2MMA0
2
LLPS-Orl-0563
ENSORLG00000024338.1
H2M8G3
3
LLPS-Orl-2370
ENSORLG00000019215.2
H2MY74
4
LLPS-Orl-1835
ENSORLG00000004880.2
A0A3B3IAF7
afap1l2
5
LLPS-Orl-0407
ENSORLG00000028103.1
H2MZ30
asz1
6
LLPS-Orl-0113
ENSORLG00000023125.1
A0A3B3IID2
casc3
7
LLPS-Orl-0141
ENSORLG00000004913.2
H2LJJ2
cd74
8
LLPS-Orl-1213
ENSORLG00000012007.2
H2M954
cenpv
9
LLPS-Orl-0868
ENSORLG00000011453.2
H2M791
cnbp
10
LLPS-Orl-3238
ENSORLG00000021763.1
Q8HLX3
COI
11
LLPS-Orl-3251
ENSORLG00000011080.2
H2M611
ctsb
12
LLPS-Orl-0710
ENSORLG00000003413.2
H2LE76
dcp1a
13
LLPS-Orl-0419
ENSORLG00000016709.2
H2MQ88
ddx1
14
LLPS-Orl-0096
ENSORLG00000020672.2
A0A3B3HMV7
ddx4
15
LLPS-Orl-0776
ENSORLG00000007454.2
H2LTD1
dhx9
16
LLPS-Orl-1034
ENSORLG00000011022.2
H2M5U0
dicer1
17
LLPS-Orl-0149
ENSORLG00000012780.2
H2MBT2
edc4
18
LLPS-Orl-0813
ENSORLG00000007614.2
Q9YIC0
eef1a
19
LLPS-Orl-3601
ENSORLG00000028334.1
A0A3B3HDT7
eno4
20
LLPS-Orl-2252
ENSORLG00000006712.2
H2LQT4
ewsr1
21
LLPS-Orl-3424
ENSORLG00000016646.2
H2MQ19
fyco1
22
LLPS-Orl-0994
ENSORLG00000006932.2
H2LRL0
hnrnph1
23
LLPS-Orl-1577
ENSORLG00000005400.2
A0A3B3HAA2
hnrnpm
24
LLPS-Orl-1351
ENSORLG00000022434.1
A0A3B3HNE6
hsp90ab1
25
LLPS-Orl-0489
ENSORLG00000004712.2
H2LIU8
igf2bp3
26
LLPS-Orl-1694
ENSORLG00000016379.2
H2MP52
ilf3
27
LLPS-Orl-2521
ENSORLG00000004652.2
H2LIM4
LAMP1
28
LLPS-Orl-2150
ENSORLG00000001719.2
H2L8G3
LOC101155625
29
LLPS-Orl-3000
ENSORLG00000004615.2
H2LIH8
LOC101156100
30
LLPS-Orl-2612
ENSORLG00000015098.2
H2MJS4
LOC101160075
31
LLPS-Orl-0120
ENSORLG00000004580.2
H2LID6
LOC101162697
32
LLPS-Orl-0955
ENSORLG00000017636.2
H2MTG9
LOC101166761
33
LLPS-Orl-0754
ENSORLG00000000292.2
A0A3B3HFQ0
LOC101168533
34
LLPS-Orl-3693
ENSORLG00000025267.1
H2M8S8
LOC101169506
35
LLPS-Orl-1136
ENSORLG00000022820.1
A0A3B3HLH0
LOC101169997
36
LLPS-Orl-0479
ENSORLG00000012435.2
H2MAL4
LOC101170313
37
LLPS-Orl-0935
ENSORLG00000018577.2
H2MWH8
LOC101171965
38
LLPS-Orl-0235
ENSORLG00000018052.2
H2MUY8
LOC101174063
39
LLPS-Orl-0798
ENSORLG00000020884.2
A0A3B3HBQ9
LOC101174409
40
LLPS-Orl-4109
ENSORLG00000014759.2
H2MIL1
LOC111946273
41
LLPS-Orl-0254
ENSORLG00000008281.2
H2LWA5
LYAR
42
LLPS-Orl-2107
ENSORLG00000007055.4
H2LS06
ncl
43
LLPS-Orl-1335
ENSORLG00000002691.2
A0A3B3HJ84
pabpc1
44
LLPS-Orl-0728
ENSORLG00000005176.2
A0A3B3HKL4
PCBP2
45
LLPS-Orl-0019
ENSORLG00000013695.2
A0A3B3HI06
piwil1
46
LLPS-Orl-1714
ENSORLG00000013656.2
H2MEW7
piwil2
47
LLPS-Orl-0570
ENSORLG00000018466.2
H2MW84
pmpcb
48
LLPS-Orl-2093
ENSORLG00000006296.2
A0A3B3I1E9
ranbp9
49
LLPS-Orl-4038
ENSORLG00000001895.2
H2L926
rangrf
50
LLPS-Orl-2626
ENSORLG00000016263.2
H2MNQ3
rbm8a
51
LLPS-Orl-4087
ENSORLG00000012818.2
H2MBX3
rnf17
52
LLPS-Orl-1519
ENSORLG00000007578.2
A0A3B3HGE4
rpl11
53
LLPS-Orl-2404
ENSORLG00000005524.2
H2LLN8
rpl23a
54
LLPS-Orl-1725
ENSORLG00000012759.2
H2MBQ4
rpl24
55
LLPS-Orl-0593
ENSORLG00000012901.2
H2MC83
rps14
56
LLPS-Orl-0108
ENSORLG00000003239.2
H2LDM6
rps8
57
LLPS-Orl-2184
ENSORLG00000003317.2
H2LDV9
smg6
58
LLPS-Orl-0971
ENSORLG00000004833.2
H2LJ98
tdrd1
59
LLPS-Orl-0531
ENSORLG00000004502.2
A0A3B3HRM3
tdrd3
60
LLPS-Orl-1636
ENSORLG00000025711.1
A0A3B3IHD6
tdrd5
61
LLPS-Orl-1426
ENSORLG00000003824.2
H2LFM0
tdrd7
62
LLPS-Orl-2632
ENSORLG00000009043.2
H2LYW8
tekt2
63
LLPS-Orl-3419
ENSORLG00000011417.2
H2M745
tekt4
64
LLPS-Orl-3750
ENSORLG00000014386.2
H2MHC8
tomm34
65
LLPS-Orl-0472
ENSORLG00000017296.2
H2MSA1
top3b
66
LLPS-Orl-0917
ENSORLG00000013780.2
H2MFB1
tra2a
67
LLPS-Orl-3028
ENSORLG00000001106.3
H2L6C7
trpm5
68
LLPS-Orl-1641
ENSORLG00000016992.2
H2MR79
ttc21b
69
LLPS-Orl-3425
ENSORLG00000029553.1
A0A3B3INE5
ubtd1
70
LLPS-Orl-2934
ENSORLG00000008453.2
H2LWX5
upf1
71
LLPS-Orl-3464
ENSORLG00000010762.2
H2M4X8
usp9x
72
LLPS-Orl-0371
ENSORLG00000017812.2
A0A3B3HL73
vim
73
LLPS-Orl-3485
ENSORLG00000010208.2
H2M305
vps26a
74
LLPS-Orl-1175
ENSORLG00000019098.2
H2MXX7
YTHDC2