Ornithorhynchus anatinus      Chromatoid body


※ Chromatoid body introduction

    A single large granule of nuage, presents in post-meiotic spermatids is called the chromatoid body (1). Multiple proteins and some mRNAs have been found to localized to the chromatoid body including mouse VASA homolog , tudor-domain containing 1 (TDRD1), tudor-domain containing 6 (TDRD6), and tudor-domain containing 7 (TDRD7) , transition protein 2 (Tnp2), RANBP9, as a known MVH interactor also localizes to it. Its formation is related to the coalescence of intermitochondrial cement granules. In fact, the formation of the chromatoid body is not required for microRNA biogenesis, but might be important for its action on target mRNAs (1). In mice, the chromatoid body is a structure resembles Gp, TDRD6 plays a role in establishing the body and the localization of piRNA pathway components to this body (2).

Reference
1. Woodruff, J. B., Hyman, A. A., & Boke, E. (2018) Organization and Function of Non-dynamic Biomolecular Condensates. Trends Biochem Sci, 43(2), 81-94. PMID: 30086300
2. Ma, L., Buchold, G. M., Greenbaum, M. P., Roy, A., Burns, K. H., Zhu, H., et al. (2009) GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet, 5(9), e1000635. PMID: 19730684


There are 80 genes.  Reviewed (0 or Unreviewed (80

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Ora-0300
ENSOANG00000011143.2
F7DG38
2
LLPS-Ora-0497
ENSOANG00000008274.3
F6XQ66
3
LLPS-Ora-0671
ENSOANG00000003874.2
F7AXG7
4
LLPS-Ora-0835
ENSOANG00000013980.2
F6URQ8
5
LLPS-Ora-0886
ENSOANG00000004888.2
F7FUC3
6
LLPS-Ora-1170
ENSOANG00000002860.3
F6U863
7
LLPS-Ora-1200
ENSOANG00000001240.1
F6YDX9
8
LLPS-Ora-1275
ENSOANG00000013012.2
F6S948
9
LLPS-Ora-1278
ENSOANG00000029102.1
K7ECS0
10
LLPS-Ora-1348
ENSOANG00000012687.3
F7A8R1
11
LLPS-Ora-1561
ENSOANG00000008732.4
F6Z6I2
12
LLPS-Ora-1596
ENSOANG00000011950.3
F7BJH8
13
LLPS-Ora-1784
ENSOANG00000007303.5
F6XWC7
14
LLPS-Ora-1877
ENSOANG00000028346.1
K7E9D7
15
LLPS-Ora-1976
ENSOANG00000008367.3
F7BRJ4
16
LLPS-Ora-2055
ENSOANG00000003499.1
F7FS51
17
LLPS-Ora-2350
ENSOANG00000021103.2
F7G5Y7
18
LLPS-Ora-2413
ENSOANG00000021432.2
F6Z2J1
19
LLPS-Ora-2451
ENSOANG00000011275.3
F7DP21
20
LLPS-Ora-2535
ENSOANG00000028519.1
K7E9M6
21
LLPS-Ora-2704
ENSOANG00000022332.1
F6TDA9
22
LLPS-Ora-3030
ENSOANG00000030557.1
K7ECX4
23
LLPS-Ora-3309
ENSOANG00000002249.2
F6STR3
24
LLPS-Ora-3480
ENSOANG00000002309.3
F7AJH7
25
LLPS-Ora-3528
ENSOANG00000030406.1
K7E9R2
26
LLPS-Ora-1619
ENSOANG00000015125.2
F6WWW2
ADAD1
27
LLPS-Ora-2837
ENSOANG00000001560.3
F7G7S1
AFAP1L2
28
LLPS-Ora-1431
ENSOANG00000007125.2
F6QQV2
AGO2
29
LLPS-Ora-0685
ENSOANG00000000585.2
F7F4D6
CNBP
30
LLPS-Ora-1921
ENSOANG00000030354.1
K7E8I5
DCP1A
31
LLPS-Ora-1471
ENSOANG00000005450.3
F7C342
DDX1
32
LLPS-Ora-2146
ENSOANG00000012968.3
F6UXL0
DDX25
33
LLPS-Ora-0025
ENSOANG00000008043.2
F7EF79
DDX5
34
LLPS-Ora-0963
ENSOANG00000012034.3
F7DMW3
DICER1
35
LLPS-Ora-0234
ENSOANG00000012299.3
F7DL66
EDC4
36
LLPS-Ora-3138
ENSOANG00000004333.2
F6S3X9
EIF4A1
37
LLPS-Ora-1538
ENSOANG00000000334.3
F7E862
EIF4A3
38
LLPS-Ora-1479
ENSOANG00000009633.3
F6Z2Z0
EIF4E
39
LLPS-Ora-2726
ENSOANG00000014244.2
F6WFL5
ELAVL1
40
LLPS-Ora-0103
ENSOANG00000014134.2
F6UQI0
ENO4
41
LLPS-Ora-2576
ENSOANG00000001304.4
F7FR65
EWSR1
42
LLPS-Ora-2807
ENSOANG00000006790.2
F6X7R4
FYCO1
43
LLPS-Ora-1251
ENSOANG00000021312.1
F6SXN6
GPX4
44
LLPS-Ora-1226
ENSOANG00000009159.4
F7EJK5
HNRNPA2B1
45
LLPS-Ora-1562
ENSOANG00000004651.2
F7FH44
HNRNPDL
46
LLPS-Ora-1452
ENSOANG00000010222.3
F7B648
HNRNPH1
47
LLPS-Ora-1295
ENSOANG00000010259.2
F6YTU7
HNRNPM
48
LLPS-Ora-2678
ENSOANG00000010249.4
F6ZKH6
HNRNPU
49
LLPS-Ora-0264
ENSOANG00000005734.4
F6X099
HSP90AA1
50
LLPS-Ora-0157
ENSOANG00000009457.2
F6ZXI7
HSPA2
51
LLPS-Ora-1152
ENSOANG00000010236.3
F7AD63
IP6K1
52
LLPS-Ora-1333
ENSOANG00000015635.3
F7G445
LAMP1
53
LLPS-Ora-3015
ENSOANG00000013836.2
F7FV54
LOC100073896
54
LLPS-Ora-3247
ENSOANG00000009156.2
F7EJM9
LOC100077443
55
LLPS-Ora-1216
ENSOANG00000011775.3
F6S5D8
LOC100078575
56
LLPS-Ora-0027
ENSOANG00000000164.1
F6PX78
LOC100093316
57
LLPS-Ora-0499
ENSOANG00000012997.5
F6T4H4
LYAR
58
LLPS-Ora-3285
ENSOANG00000019378.1
Q36452
MT-CO1
59
LLPS-Ora-1521
ENSOANG00000006600.3
F6R2D4
NEDD1
60
LLPS-Ora-0485
ENSOANG00000007307.3
F6XVK7
PABPC1
61
LLPS-Ora-0403
ENSOANG00000010778.2
F6X4I7
PIWIL2
62
LLPS-Ora-0226
ENSOANG00000006975.3
F7D8G8
RANBP9
63
LLPS-Ora-0932
ENSOANG00000000321.3
F7EFX6
RPL11
64
LLPS-Ora-2514
ENSOANG00000009558.2
F6S1W8
RPL23A
65
LLPS-Ora-1654
ENSOANG00000007505.3
F6PPT9
RPL24
66
LLPS-Ora-0141
ENSOANG00000003202.2
F6Y382
RPS14
67
LLPS-Ora-0417
ENSOANG00000012229.2
F7FGW0
SMG1
68
LLPS-Ora-0520
ENSOANG00000020536.2
F7EUY2
SRSF3
69
LLPS-Ora-1988
ENSOANG00000014200.2
F7BHW8
STK31
70
LLPS-Ora-1370
ENSOANG00000001562.3
F7G7H9
TDRD1
71
LLPS-Ora-0260
ENSOANG00000000964.3
F6YH90
TDRD5
72
LLPS-Ora-2484
ENSOANG00000000797.2
F6QHP7
TDRD9
73
LLPS-Ora-1729
ENSOANG00000002075.2
F6ZVI6
TEKT2
74
LLPS-Ora-1410
ENSOANG00000015785.4
F7FXJ5
TNPO1
75
LLPS-Ora-1545
ENSOANG00000007672.2
F6W8X0
TNRC6A
76
LLPS-Ora-1456
ENSOANG00000013953.3
F7DAK4
TRA2B
77
LLPS-Ora-0551
ENSOANG00000006223.3
F6VWR7
TTC21B
78
LLPS-Ora-0786
ENSOANG00000003463.2
F7D6H9
UBTD1
79
LLPS-Ora-1328
ENSOANG00000004568.2
F7E550
UPF1
80
LLPS-Ora-3251
ENSOANG00000004188.3
F6TWU6
VPS26A