Oreochromis niloticus      Chromatoid body


※ Chromatoid body introduction

    A single large granule of nuage, presents in post-meiotic spermatids is called the chromatoid body (1). Multiple proteins and some mRNAs have been found to localized to the chromatoid body including mouse VASA homolog , tudor-domain containing 1 (TDRD1), tudor-domain containing 6 (TDRD6), and tudor-domain containing 7 (TDRD7) , transition protein 2 (Tnp2), RANBP9, as a known MVH interactor also localizes to it. Its formation is related to the coalescence of intermitochondrial cement granules. In fact, the formation of the chromatoid body is not required for microRNA biogenesis, but might be important for its action on target mRNAs (1). In mice, the chromatoid body is a structure resembles Gp, TDRD6 plays a role in establishing the body and the localization of piRNA pathway components to this body (2).

Reference
1. Woodruff, J. B., Hyman, A. A., & Boke, E. (2018) Organization and Function of Non-dynamic Biomolecular Condensates. Trends Biochem Sci, 43(2), 81-94. PMID: 30086300
2. Ma, L., Buchold, G. M., Greenbaum, M. P., Roy, A., Burns, K. H., Zhu, H., et al. (2009) GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet, 5(9), e1000635. PMID: 19730684


There are 78 genes.  Reviewed (1 or Unreviewed (77

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Orn-0302
ENSONIG00000020768.1
P62796
2
LLPS-Orn-0057
ENSONIG00000017753.1
I3KMN8
3
LLPS-Orn-0114
ENSONIG00000010424.1
I3JW57
4
LLPS-Orn-0196
ENSONIG00000003909.1
I3J7T6
5
LLPS-Orn-0345
ENSONIG00000002717.1
I3J3G6
6
LLPS-Orn-0349
ENSONIG00000009439.1
I3JSL5
7
LLPS-Orn-0620
ENSONIG00000001218.1
I3IY50
8
LLPS-Orn-0651
ENSONIG00000001471.1
I3IZ08
9
LLPS-Orn-0823
ENSONIG00000011151.1
I3JYU5
10
LLPS-Orn-0965
ENSONIG00000011113.1
I3JYP4
11
LLPS-Orn-1061
ENSONIG00000005417.1
I3JD66
12
LLPS-Orn-1100
ENSONIG00000020126.1
I3KW58
13
LLPS-Orn-1129
ENSONIG00000004224.1
I3J8X5
14
LLPS-Orn-1167
ENSONIG00000017668.1
I3KMD3
15
LLPS-Orn-1273
ENSONIG00000002527.1
I3J2S4
16
LLPS-Orn-1299
ENSONIG00000000269.1
I3IUQ3
17
LLPS-Orn-1329
ENSONIG00000006851.1
I3JIF2
18
LLPS-Orn-1495
ENSONIG00000007705.1
I3JLG7
19
LLPS-Orn-1739
ENSONIG00000009141.1
I3JRJ8
20
LLPS-Orn-1778
ENSONIG00000016203.1
I3KH09
21
LLPS-Orn-1906
ENSONIG00000002122.1
I3J1A5
22
LLPS-Orn-1993
ENSONIG00000000513.1
I3IVL5
23
LLPS-Orn-2003
ENSONIG00000009337.1
I3JS90
24
LLPS-Orn-2157
ENSONIG00000001405.1
I3IYT2
25
LLPS-Orn-2295
ENSONIG00000005493.1
I3JDG2
26
LLPS-Orn-2357
ENSONIG00000001260.1
I3IY99
27
LLPS-Orn-2809
ENSONIG00000004860.1
I3JB75
28
LLPS-Orn-2870
ENSONIG00000005936.1
I3JF31
29
LLPS-Orn-2874
ENSONIG00000010563.1
I3JWN6
30
LLPS-Orn-3508
ENSONIG00000008521.1
I3JPC0
31
LLPS-Orn-3542
ENSONIG00000001096.1
I3IXP7
32
LLPS-Orn-0289
ENSONIG00000016389.1
I3KHP5
afap1l2
33
LLPS-Orn-1936
ENSONIG00000013056.1
I3K5M3
cd74
34
LLPS-Orn-3224
ENSONIG00000014085.1
I3K9B0
CENPVL1
35
LLPS-Orn-0208
ENSONIG00000018269.1
I3KPF9
DDX5
36
LLPS-Orn-0478
ENSONIG00000000293.1
I3IUS8
dhx9
37
LLPS-Orn-1290
ENSONIG00000019828.1
I3KV15
eif4a3
38
LLPS-Orn-0112
ENSONIG00000019485.1
I3KTT3
eif4e
39
LLPS-Orn-3367
ENSONIG00000017754.1
I3KMN9
hnrnph1
40
LLPS-Orn-3674
ENSONIG00000004506.1
I3J9Y3
igf2bp3
41
LLPS-Orn-0723
ENSONIG00000003203.1
I3J577
LAMP1
42
LLPS-Orn-4015
ENSONIG00000014546.1
I3KB11
LOC100534427
43
LLPS-Orn-1000
ENSONIG00000008977.1
I3JQZ4
LOC100691481
44
LLPS-Orn-0023
ENSONIG00000001448.1
I3IYY1
LOC100692041
45
LLPS-Orn-0747
ENSONIG00000000606.1
I3IVY1
LOC100693841
46
LLPS-Orn-1873
ENSONIG00000018907.1
I3KRR2
LOC100694805
47
LLPS-Orn-3504
ENSONIG00000019734.1
I3KUP5
LOC100700609
48
LLPS-Orn-2734
ENSONIG00000000805.1
I3IWN4
LOC100701982
49
LLPS-Orn-1549
ENSONIG00000017003.1
I3KJZ8
LOC100702237
50
LLPS-Orn-1874
ENSONIG00000017101.1
I3KKC0
LOC100707845
51
LLPS-Orn-0066
ENSONIG00000010747.1
I3JXB7
LOC100708747
52
LLPS-Orn-1613
ENSONIG00000020366.1
I3KX19
lyar
53
LLPS-Orn-1366
ENSONIG00000012508.1
I3K3Q2
ncl
54
LLPS-Orn-0407
ENSONIG00000010951.1
I3JY33
piwil1
55
LLPS-Orn-0270
ENSONIG00000011121.1
I3JYQ7
piwil2
56
LLPS-Orn-0046
ENSONIG00000008066.1
I3JMR6
pmpcb
57
LLPS-Orn-2816
ENSONIG00000017484.1
I3KLQ6
PSIP1
58
LLPS-Orn-2637
ENSONIG00000020824.1
I3KYD1
rangrf
59
LLPS-Orn-1138
ENSONIG00000008608.1
I3JPM9
rbm8a
60
LLPS-Orn-2608
ENSONIG00000015746.1
I3KFC1
rnf17
61
LLPS-Orn-1374
ENSONIG00000004876.1
I3JB93
rpl23a
62
LLPS-Orn-1765
ENSONIG00000014266.1
I3K9Y8
rpl24
63
LLPS-Orn-0429
ENSONIG00000017838.1
I3KMZ3
rps14
64
LLPS-Orn-0656
ENSONIG00000018356.1
I3KPR7
rps8
65
LLPS-Orn-1201
ENSONIG00000003445.1
I3J647
smg1
66
LLPS-Orn-1523
ENSONIG00000005594.1
I3JDU9
smg6
67
LLPS-Orn-3467
ENSONIG00000016382.1
I3KHN6
tdrd1
68
LLPS-Orn-3479
ENSONIG00000003233.1
I3J5C0
tdrd3
69
LLPS-Orn-2262
ENSONIG00000014143.1
I3K9I6
tdrd5
70
LLPS-Orn-0600
ENSONIG00000013766.1
I3K871
tekt2
71
LLPS-Orn-3420
ENSONIG00000015699.1
I3KF62
tnrc6a
72
LLPS-Orn-1646
ENSONIG00000010464.1
I3JWA9
top3b
73
LLPS-Orn-2058
ENSONIG00000009025.1
I3JR56
TRA2B
74
LLPS-Orn-0171
ENSONIG00000005867.1
I3JEU6
trpm5
75
LLPS-Orn-3926
ENSONIG00000008858.1
I3JQJ2
ttc21b
76
LLPS-Orn-0047
ENSONIG00000012729.1
I3K4H4
upf1
77
LLPS-Orn-2139
ENSONIG00000009246.1
I3JRY2
vim
78
LLPS-Orn-0572
ENSONIG00000011601.1
I3K0G5
YTHDC2