Monodelphis domestica      Chromatoid body


※ Chromatoid body introduction

    A single large granule of nuage, presents in post-meiotic spermatids is called the chromatoid body (1). Multiple proteins and some mRNAs have been found to localized to the chromatoid body including mouse VASA homolog , tudor-domain containing 1 (TDRD1), tudor-domain containing 6 (TDRD6), and tudor-domain containing 7 (TDRD7) , transition protein 2 (Tnp2), RANBP9, as a known MVH interactor also localizes to it. Its formation is related to the coalescence of intermitochondrial cement granules. In fact, the formation of the chromatoid body is not required for microRNA biogenesis, but might be important for its action on target mRNAs (1). In mice, the chromatoid body is a structure resembles Gp, TDRD6 plays a role in establishing the body and the localization of piRNA pathway components to this body (2).

Reference
1. Woodruff, J. B., Hyman, A. A., & Boke, E. (2018) Organization and Function of Non-dynamic Biomolecular Condensates. Trends Biochem Sci, 43(2), 81-94. PMID: 30086300
2. Ma, L., Buchold, G. M., Greenbaum, M. P., Roy, A., Burns, K. H., Zhu, H., et al. (2009) GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet, 5(9), e1000635. PMID: 19730684


There are 96 genes.  Reviewed (0 or Unreviewed (96

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Mod-0105
ENSMODG00000017748.3
F7E551
2
LLPS-Mod-0286
ENSMODG00000009436.3
F7AYT6
3
LLPS-Mod-0840
ENSMODG00000023092.2
F6ZPS1
4
LLPS-Mod-0906
ENSMODG00000014781.3
F7G6X8
5
LLPS-Mod-1013
ENSMODG00000005486.2
F7BXY9
6
LLPS-Mod-1593
ENSMODG00000011213.2
F6SQ78
7
LLPS-Mod-2171
ENSMODG00000003801.3
F6ZK16
8
LLPS-Mod-2195
ENSMODG00000006684.2
F7FFI8
9
LLPS-Mod-2196
ENSMODG00000016415.2
F7AT41
10
LLPS-Mod-2324
ENSMODG00000018933.2
F7GJQ3
11
LLPS-Mod-2448
ENSMODG00000004888.4
F7C2K2
12
LLPS-Mod-2572
ENSMODG00000008679.3
F6PFT3
13
LLPS-Mod-3138
ENSMODG00000016196.3
F7FY89
14
LLPS-Mod-3233
ENSMODG00000013302.2
F6ZJA5
15
LLPS-Mod-3343
ENSMODG00000005901.3
F6XD73
16
LLPS-Mod-3453
ENSMODG00000007943.2
F7G8Z2
17
LLPS-Mod-3915
ENSMODG00000008668.2
F6PFZ8
18
LLPS-Mod-1627
ENSMODG00000018918.3
F7GK10
ADAD1
19
LLPS-Mod-4293
ENSMODG00000009761.3
F6WT41
AFAP1L2
20
LLPS-Mod-2020
ENSMODG00000000748.3
F6VPM9
AGO2
21
LLPS-Mod-3800
ENSMODG00000011265.4
F6PK57
AKAP4
22
LLPS-Mod-3503
ENSMODG00000015784.3
F6Z443
ASZ1
23
LLPS-Mod-2025
ENSMODG00000013044.4
F7G173
CASC3
24
LLPS-Mod-0408
ENSMODG00000028756.1
K7E537
CD74
25
LLPS-Mod-1644
ENSMODG00000008362.3
F7EJM5
CNBP
26
LLPS-Mod-2996
ENSMODG00000021572.1
Q65CJ1
COI
27
LLPS-Mod-3606
ENSMODG00000012029.1
F7ALZ4
CTSB
28
LLPS-Mod-3152
ENSMODG00000012554.3
F6PLR3
DCP1A
29
LLPS-Mod-1449
ENSMODG00000010275.2
F6VNU2
DDX1
30
LLPS-Mod-1946
ENSMODG00000004275.3
F6TEM9
DDX25
31
LLPS-Mod-2769
ENSMODG00000019511.3
F6VDB2
DDX4
32
LLPS-Mod-1211
ENSMODG00000003743.2
F7ECU0
DDX5
33
LLPS-Mod-1937
ENSMODG00000006955.3
F6QW04
DHX9
34
LLPS-Mod-0673
ENSMODG00000012624.3
F6RSN3
DICER1
35
LLPS-Mod-0924
ENSMODG00000005510.3
F7G5P8
EDC4
36
LLPS-Mod-0560
ENSMODG00000007090.2
F6UEF7
EIF4A1
37
LLPS-Mod-0262
ENSMODG00000002190.2
F7GE48
EIF4A3
38
LLPS-Mod-0473
ENSMODG00000020716.3
F7BAD4
EIF4E
39
LLPS-Mod-0611
ENSMODG00000005041.3
F7BEV0
ELAVL1
40
LLPS-Mod-2842
ENSMODG00000009486.3
F7FN99
ENO4
41
LLPS-Mod-3919
ENSMODG00000006483.1
F7F2V0
FABP9
42
LLPS-Mod-3844
ENSMODG00000011432.4
F6RJR8
FYCO1
43
LLPS-Mod-0382
ENSMODG00000000603.3
F6TBC0
HNRNPA2B1
44
LLPS-Mod-0836
ENSMODG00000011916.3
F7E028
HNRNPDL
45
LLPS-Mod-2374
ENSMODG00000006515.3
F7E3Z9
HNRNPU
46
LLPS-Mod-0817
ENSMODG00000023945.1
F6V652
HSPA2
47
LLPS-Mod-2605
ENSMODG00000001014.3
F6ZFA4
IGF2BP3
48
LLPS-Mod-0193
ENSMODG00000005911.3
F6XCW7
ILF3
49
LLPS-Mod-2449
ENSMODG00000012903.4
F7GKX9
IP6K1
50
LLPS-Mod-0593
ENSMODG00000017551.2
F7E0Y6
KHDRBS1
51
LLPS-Mod-0231
ENSMODG00000003894.2
F7D889
LAMP1
52
LLPS-Mod-3758
ENSMODG00000006522.2
Q9XT87
LDHA
53
LLPS-Mod-2210
ENSMODG00000000653.2
F6STW5
LOC100010620
54
LLPS-Mod-0671
ENSMODG00000003838.2
F7EBQ9
LOC100013511
55
LLPS-Mod-0478
ENSMODG00000015173.2
F6XFE0
LOC100023597
56
LLPS-Mod-1595
ENSMODG00000001500.5
K7E0U0
LYAR
57
LLPS-Mod-1309
ENSMODG00000002482.3
F7BVW2
MAEL
58
LLPS-Mod-2523
ENSMODG00000002470.4
F7BWB5
NCL
59
LLPS-Mod-1331
ENSMODG00000007794.3
F7A8H9
NEDD1
60
LLPS-Mod-1104
ENSMODG00000006222.3
F7FS75
PABPC1
61
LLPS-Mod-0399
ENSMODG00000015619.3
F6YFN1
PIWIL1
62
LLPS-Mod-3257
ENSMODG00000009482.3
F7FNI0
PIWIL2
63
LLPS-Mod-2302
ENSMODG00000017224.3
F6WXQ5
PMPCB
64
LLPS-Mod-2799
ENSMODG00000014943.3
F7FIE3
PSIP1
65
LLPS-Mod-1259
ENSMODG00000007884.3
F6ZH16
RBM14
66
LLPS-Mod-0759
ENSMODG00000018752.3
F7EF23
RBM8A
67
LLPS-Mod-2488
ENSMODG00000007827.3
F7ETJ9
RNF17
68
LLPS-Mod-0600
ENSMODG00000012828.3
F7DD44
RPL11
69
LLPS-Mod-0035
ENSMODG00000001916.1
F6W129
RPL24
70
LLPS-Mod-1137
ENSMODG00000009485.3
F7FN91
RPS14
71
LLPS-Mod-0709
ENSMODG00000028389.1
K7E2H0
RPS8
72
LLPS-Mod-2015
ENSMODG00000006102.3
F7F0R6
SMG1
73
LLPS-Mod-2269
ENSMODG00000010622.3
F7DPA4
SMG6
74
LLPS-Mod-3067
ENSMODG00000014955.3
F7D0F1
SPERT
75
LLPS-Mod-1887
ENSMODG00000013539.3
F7CM23
SRSF3
76
LLPS-Mod-0057
ENSMODG00000000777.3
F6SSP4
STK31
77
LLPS-Mod-2778
ENSMODG00000009788.3
F6SZ89
TDRD1
78
LLPS-Mod-1412
ENSMODG00000006316.3
F7B4G6
TDRD3
79
LLPS-Mod-1016
ENSMODG00000006180.3
F7B4W0
TDRD5
80
LLPS-Mod-0383
ENSMODG00000018889.3
F7CR83
TDRD6
81
LLPS-Mod-2414
ENSMODG00000003093.3
F6PIW4
TDRD7
82
LLPS-Mod-0663
ENSMODG00000013609.3
F6VF39
TDRD9
83
LLPS-Mod-0076
ENSMODG00000017883.3
F7GFM8
TEKT2
84
LLPS-Mod-0725
ENSMODG00000016913.3
F6VNC9
TEKT4
85
LLPS-Mod-4325
ENSMODG00000016348.4
F7F790
TNRC6A
86
LLPS-Mod-3110
ENSMODG00000017702.3
F7FUS9
TOP3B
87
LLPS-Mod-2537
ENSMODG00000013248.4
F7DUM8
TRA2B
88
LLPS-Mod-1640
ENSMODG00000006501.3
F7EKI1
TTC21B
89
LLPS-Mod-1858
ENSMODG00000023336.2
F6V4Z9
TUBA3E
90
LLPS-Mod-0305
ENSMODG00000003689.3
F7FAH9
UPF1
91
LLPS-Mod-4401
ENSMODG00000021098.3
F6UID4
USP9X
92
LLPS-Mod-3260
ENSMODG00000009818.3
F6SFE6
VIM
93
LLPS-Mod-1277
ENSMODG00000010661.3
H9H6E3
VPS26A
94
LLPS-Mod-4112
ENSMODG00000012784.3
F6S0U4
VPS35
95
LLPS-Mod-0720
ENSMODG00000017596.5
H9H739
YBX2
96
LLPS-Mod-0365
ENSMODG00000015671.3
F7EI44
YTHDC2