Meleagris gallopavo      Chromatoid body


※ Chromatoid body introduction

    A single large granule of nuage, presents in post-meiotic spermatids is called the chromatoid body (1). Multiple proteins and some mRNAs have been found to localized to the chromatoid body including mouse VASA homolog , tudor-domain containing 1 (TDRD1), tudor-domain containing 6 (TDRD6), and tudor-domain containing 7 (TDRD7) , transition protein 2 (Tnp2), RANBP9, as a known MVH interactor also localizes to it. Its formation is related to the coalescence of intermitochondrial cement granules. In fact, the formation of the chromatoid body is not required for microRNA biogenesis, but might be important for its action on target mRNAs (1). In mice, the chromatoid body is a structure resembles Gp, TDRD6 plays a role in establishing the body and the localization of piRNA pathway components to this body (2).

Reference
1. Woodruff, J. B., Hyman, A. A., & Boke, E. (2018) Organization and Function of Non-dynamic Biomolecular Condensates. Trends Biochem Sci, 43(2), 81-94. PMID: 30086300
2. Ma, L., Buchold, G. M., Greenbaum, M. P., Roy, A., Burns, K. H., Zhu, H., et al. (2009) GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet, 5(9), e1000635. PMID: 19730684


There are 72 genes.  Reviewed (0 or Unreviewed (72

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Meg-0062
ENSMGAG00000000617.2
G3USQ3
2
LLPS-Meg-0121
ENSMGAG00000016129.1
G1NS60
3
LLPS-Meg-0133
ENSMGAG00000008093.1
H9H1D4
4
LLPS-Meg-0780
ENSMGAG00000014281.2
G1NN94
5
LLPS-Meg-1069
ENSMGAG00000011537.2
G1NG83
6
LLPS-Meg-1752
ENSMGAG00000006527.1
G1N431
7
LLPS-Meg-2121
ENSMGAG00000008204.2
G1N800
8
LLPS-Meg-2321
ENSMGAG00000005401.2
G1N1E7
9
LLPS-Meg-2759
ENSMGAG00000011055.1
G1NEY3
10
LLPS-Meg-2808
ENSMGAG00000014611.1
G1NP45
11
LLPS-Meg-3160
ENSMGAG00000012316.1
G1NI89
12
LLPS-Meg-3226
ENSMGAG00000016700.1
G3US34
13
LLPS-Meg-3175
ENSMGAG00000011077.2
G1NF13
AFAP1L2
14
LLPS-Meg-1408
ENSMGAG00000012942.1
G1NJV1
AGO2
15
LLPS-Meg-1398
ENSMGAG00000013247.1
G1NKN0
CASC3
16
LLPS-Meg-2301
ENSMGAG00000006589.2
G1N4A4
CD74
17
LLPS-Meg-2700
ENSMGAG00000017450.2
A9XBE1
COX1
18
LLPS-Meg-2331
ENSMGAG00000014216.2
G1NN37
CTSB
19
LLPS-Meg-0229
ENSMGAG00000010618.1
P67882
CYC
20
LLPS-Meg-0618
ENSMGAG00000005731.2
G1N267
DCP1A
21
LLPS-Meg-1520
ENSMGAG00000014025.2
G1NML8
DDX1
22
LLPS-Meg-0142
ENSMGAG00000007667.2
G1N6U2
DDX5
23
LLPS-Meg-0053
ENSMGAG00000013207.1
G1NKJ0
DICER1
24
LLPS-Meg-0112
ENSMGAG00000002644.2
G1MUR8
EDC4
25
LLPS-Meg-1953
ENSMGAG00000011171.2
G1NF97
EIF4E
26
LLPS-Meg-3073
ENSMGAG00000011230.2
G1NFF3
ENO4
27
LLPS-Meg-0473
ENSMGAG00000005282.2
G3USZ2
EWSR1
28
LLPS-Meg-0608
ENSMGAG00000003788.2
G1MXG3
GPX4
29
LLPS-Meg-0295
ENSMGAG00000010635.1
G1NDW3
HNRNPA2B1
30
LLPS-Meg-1970
ENSMGAG00000008033.2
G1N7L1
HNRNPDL
31
LLPS-Meg-1179
ENSMGAG00000007328.2
G1N620
HNRNPH1
32
LLPS-Meg-0910
ENSMGAG00000011427.2
G1NG01
HNRNPU
33
LLPS-Meg-1913
ENSMGAG00000013355.2
G1NKX1
HSP90AA1
34
LLPS-Meg-1925
ENSMGAG00000010808.2
G1NEA9
HSP90AB1
35
LLPS-Meg-2738
ENSMGAG00000015391.1
G1NR17
HSPA2
36
LLPS-Meg-0967
ENSMGAG00000010497.2
G1NDI3
IGF2BP3
37
LLPS-Meg-1416
ENSMGAG00000003155.1
G1MVY4
IP6K1
38
LLPS-Meg-0345
ENSMGAG00000014850.2
G1NPR7
LAMP1
39
LLPS-Meg-1618
ENSMGAG00000007372.1
G1N679
LDHA
40
LLPS-Meg-0377
ENSMGAG00000015703.2
G1NRJ0
LOC104916664
41
LLPS-Meg-1311
ENSMGAG00000012703.2
G1NJ94
LYAR
42
LLPS-Meg-1616
ENSMGAG00000014437.2
G1NNP4
MAEL
43
LLPS-Meg-2928
ENSMGAG00000012239.2
G1NI21
PABPC1
44
LLPS-Meg-0202
ENSMGAG00000002382.1
G1MU43
PIWIL1
45
LLPS-Meg-0388
ENSMGAG00000006213.2
G1N3F4
PMPCB
46
LLPS-Meg-2905
ENSMGAG00000005593.2
G1N1T2
PSIP1
47
LLPS-Meg-0693
ENSMGAG00000002794.2
G1MV31
RANBP9
48
LLPS-Meg-2711
ENSMGAG00000015138.2
G1NQG5
RNF17
49
LLPS-Meg-1587
ENSMGAG00000005572.2
G1N1S2
RPL11
50
LLPS-Meg-1781
ENSMGAG00000012800.2
H9H1W1
RPL23A
51
LLPS-Meg-0709
ENSMGAG00000014373.1
G1NNI3
RPL24
52
LLPS-Meg-0331
ENSMGAG00000006575.1
G1N479
RPS14
53
LLPS-Meg-1805
ENSMGAG00000010142.1
G1NCM9
RPS8
54
LLPS-Meg-0306
ENSMGAG00000007757.1
G1N769
SMG1
55
LLPS-Meg-1748
ENSMGAG00000002503.1
G1MUB1
SRSF3
56
LLPS-Meg-2128
ENSMGAG00000010548.1
G1NDN0
STK31
57
LLPS-Meg-0888
ENSMGAG00000011067.2
G5E7M1
TDRD1
58
LLPS-Meg-0782
ENSMGAG00000014961.2
G1NQ11
TDRD3
59
LLPS-Meg-0042
ENSMGAG00000008737.2
G1N9C0
TDRD7
60
LLPS-Meg-2318
ENSMGAG00000013431.2
G1NL37
TDRD9
61
LLPS-Meg-0790
ENSMGAG00000003750.1
G1MXD4
TEKT2
62
LLPS-Meg-2840
ENSMGAG00000005330.2
G1N166
TEKT4
63
LLPS-Meg-2199
ENSMGAG00000003654.1
G1MX46
TOMM34
64
LLPS-Meg-2008
ENSMGAG00000001002.2
G1MQQ8
TOP3B
65
LLPS-Meg-0885
ENSMGAG00000002853.2
G1MV83
TRA2B
66
LLPS-Meg-1135
ENSMGAG00000007819.1
G1N756
TRPM5
67
LLPS-Meg-1005
ENSMGAG00000010744.2
G3UPS4
TTC21B
68
LLPS-Meg-1602
ENSMGAG00000003447.2
G1MWL0
UBTD2
69
LLPS-Meg-2717
ENSMGAG00000004745.2
G1MZU2
UPF1
70
LLPS-Meg-0949
ENSMGAG00000007735.2
G1N6W4
VIM
71
LLPS-Meg-2832
ENSMGAG00000004241.2
G1MYI5
VPS26A
72
LLPS-Meg-0193
ENSMGAG00000005283.1
G1N129
VPS35