Macaca mulatta      Chromatoid body


※ Chromatoid body introduction

    A single large granule of nuage, presents in post-meiotic spermatids is called the chromatoid body (1). Multiple proteins and some mRNAs have been found to localized to the chromatoid body including mouse VASA homolog , tudor-domain containing 1 (TDRD1), tudor-domain containing 6 (TDRD6), and tudor-domain containing 7 (TDRD7) , transition protein 2 (Tnp2), RANBP9, as a known MVH interactor also localizes to it. Its formation is related to the coalescence of intermitochondrial cement granules. In fact, the formation of the chromatoid body is not required for microRNA biogenesis, but might be important for its action on target mRNAs (1). In mice, the chromatoid body is a structure resembles Gp, TDRD6 plays a role in establishing the body and the localization of piRNA pathway components to this body (2).

Reference
1. Woodruff, J. B., Hyman, A. A., & Boke, E. (2018) Organization and Function of Non-dynamic Biomolecular Condensates. Trends Biochem Sci, 43(2), 81-94. PMID: 30086300
2. Ma, L., Buchold, G. M., Greenbaum, M. P., Roy, A., Burns, K. H., Zhu, H., et al. (2009) GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet, 5(9), e1000635. PMID: 19730684


There are 98 genes.  Reviewed (0 or Unreviewed (98

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Mam-1377
ENSMMUG00000031876.2
F7GX65
2
LLPS-Mam-2098
ENSMMUG00000029549.2
F7G769
3
LLPS-Mam-2768
ENSMMUG00000013388.3
A0A1D5RAY2
4
LLPS-Mam-2821
ENSMMUG00000043117.1
A0A1D5QUY9
5
LLPS-Mam-2962
ENSMMUG00000016086.3
A0A1D5QC84
6
LLPS-Mam-4111
ENSMMUG00000004572.3
F7H901
ADAD1
7
LLPS-Mam-4700
ENSMMUG00000019188.3
F6QYM6
ADAD2
8
LLPS-Mam-0078
ENSMMUG00000022523.3
A0A1D5RGB8
AFAP1L2
9
LLPS-Mam-0317
ENSMMUG00000008045.3
A0A1D5QH79
AGO2
10
LLPS-Mam-4283
ENSMMUG00000023060.3
F6V020
AKAP4
11
LLPS-Mam-2579
ENSMMUG00000021726.3
F7E3A1
ASZ1
12
LLPS-Mam-3769
ENSMMUG00000045187.1
A0A1D5QGZ6
CASC3
13
LLPS-Mam-3620
ENSMMUG00000009113.3
F7E9S4
CD74
14
LLPS-Mam-0390
ENSMMUG00000004896.3
F7CJK3
CENPV
15
LLPS-Mam-1693
ENSMMUG00000011585.3
F6PPB3
CNBP
16
LLPS-Mam-2332
ENSMMUG00000028689.2
I3W8K0
COX1
17
LLPS-Mam-2363
ENSMMUG00000019212.3
A0A1D5QVT4
CTSB
18
LLPS-Mam-2642
ENSMMUG00000011208.3
A0A1D5Q7U9
DCP1A
19
LLPS-Mam-0999
ENSMMUG00000023437.3
A0A1D5REB1
DDX1
20
LLPS-Mam-0245
ENSMMUG00000007624.3
F7AQN6
DDX25
21
LLPS-Mam-1012
ENSMMUG00000017386.3
A0A1D5R0N7
DDX4
22
LLPS-Mam-2901
ENSMMUG00000009463.3
F7A985
DDX5
23
LLPS-Mam-0825
ENSMMUG00000005635.3
F6W5Y4
DHX9
24
LLPS-Mam-0048
ENSMMUG00000023305.3
F6SLC3
DICER1
25
LLPS-Mam-0915
ENSMMUG00000011888.3
F7HN31
EDC4
26
LLPS-Mam-0072
ENSMMUG00000013499.3
A0A1D5Q0T7
EIF4A1
27
LLPS-Mam-0016
ENSMMUG00000009590.2
F7AD80
EIF4A3
28
LLPS-Mam-1484
ENSMMUG00000011066.3
A0A1D5QY25
EIF4E
29
LLPS-Mam-0886
ENSMMUG00000006544.3
F7HS28
ELAVL1
30
LLPS-Mam-4673
ENSMMUG00000007575.3
F6SSS8
ENO4
31
LLPS-Mam-2464
ENSMMUG00000021374.3
F7FI06
EWSR1
32
LLPS-Mam-2513
ENSMMUG00000020095.2
F7GMK2
FABP9
33
LLPS-Mam-4507
ENSMMUG00000023585.3
A0A1D5Q4E7
FYCO1
34
LLPS-Mam-1910
ENSMMUG00000028946.2
A0A1D5QPA6
GPX4
35
LLPS-Mam-2026
ENSMMUG00000038737.1
G7MQV4
HIST1H2BA
36
LLPS-Mam-1428
ENSMMUG00000003619.3
I2CYL4
HNRNPA2B1
37
LLPS-Mam-3469
ENSMMUG00000001858.3
A0A1D5QW22
HNRNPA3
38
LLPS-Mam-1315
ENSMMUG00000020982.3
F6UEF5
HNRNPF
39
LLPS-Mam-2725
ENSMMUG00000010843.3
F7G3L4
HNRNPH1
40
LLPS-Mam-3425
ENSMMUG00000018806.3
F6ZI22
HNRNPM
41
LLPS-Mam-0815
ENSMMUG00000021098.3
F7GWA9
HNRNPU
42
LLPS-Mam-1710
ENSMMUG00000000492.3
F7D4C9
HSPA2
43
LLPS-Mam-0004
ENSMMUG00000014673.3
F7FLC1
ILF3
44
LLPS-Mam-3773
ENSMMUG00000014589.3
F7GRE2
IP6K1
45
LLPS-Mam-2131
ENSMMUG00000009790.3
F6Y0V7
LAMP1
46
LLPS-Mam-3159
ENSMMUG00000031024.2
F6R1N2
LDHA
47
LLPS-Mam-1622
ENSMMUG00000032119.2
F7HAP8
LOC107000818
48
LLPS-Mam-4245
ENSMMUG00000037912.1
F7BRX2
LOC698105
49
LLPS-Mam-1567
ENSMMUG00000023393.3
F7DZD6
LYAR
50
LLPS-Mam-0984
ENSMMUG00000023463.3
F7B842
MAEL
51
LLPS-Mam-0366
ENSMMUG00000018094.3
H9H3Z4
NCL
52
LLPS-Mam-0267
ENSMMUG00000004093.3
F6TTW3
NEDD1
53
LLPS-Mam-2003
ENSMMUG00000002108.3
F6UXN0
ODF1
54
LLPS-Mam-1121
ENSMMUG00000017786.3
F7EU16
PABPC1
55
LLPS-Mam-0465
ENSMMUG00000038295.1
G7NA92
PCBP1
56
LLPS-Mam-0784
ENSMMUG00000005629.3
F7G629
PIWIL1
57
LLPS-Mam-0039
ENSMMUG00000014438.3
E1AWN8
PIWIL2
58
LLPS-Mam-1745
ENSMMUG00000003429.3
F7F9E1
PMPCB
59
LLPS-Mam-4279
ENSMMUG00000002224.3
H9ETF8
PSIP1
60
LLPS-Mam-1667
ENSMMUG00000020122.3
F7GHV7
RANBP9
61
LLPS-Mam-2630
ENSMMUG00000013540.3
F7FV40
RANGRF
62
LLPS-Mam-2211
ENSMMUG00000020363.3
G7NC47
RBM14
63
LLPS-Mam-0415
ENSMMUG00000016051.2
F7GPQ9
RBM8A
64
LLPS-Mam-0916
ENSMMUG00000001657.3
F7G6N3
RNASE6
65
LLPS-Mam-4521
ENSMMUG00000014610.3
A0A1D5RJU5
RNF17
66
LLPS-Mam-0348
ENSMMUG00000002445.3
F6PJ30
RPL11
67
LLPS-Mam-2167
ENSMMUG00000015059.3
A0A1D5QTK5
RPL24
68
LLPS-Mam-0501
ENSMMUG00000002848.3
F7HI21
RPS14
69
LLPS-Mam-0534
ENSMMUG00000015270.3
F7DV33
RPS8
70
LLPS-Mam-2358
ENSMMUG00000022441.3
A0A1D5R8H3
SMG1
71
LLPS-Mam-3891
ENSMMUG00000023161.3
F7FDL6
SMG6
72
LLPS-Mam-3025
ENSMMUG00000011986.3
F7H245
SPERT
73
LLPS-Mam-3610
ENSMMUG00000004725.3
F6R520
SRSF1
74
LLPS-Mam-0043
ENSMMUG00000014306.3
F7BSI5
SRSF3
75
LLPS-Mam-4731
ENSMMUG00000023196.3
F7EF21
STK31
76
LLPS-Mam-2413
ENSMMUG00000022517.3
F6YHU8
TDRD1
77
LLPS-Mam-0347
ENSMMUG00000007169.3
F7FJN3
TDRD3
78
LLPS-Mam-4113
ENSMMUG00000016033.3
F7FRH2
TDRD5
79
LLPS-Mam-0742
ENSMMUG00000019252.3
F7GTW6
TDRD6
80
LLPS-Mam-0961
ENSMMUG00000012275.3
H9EVV9
TDRD7
81
LLPS-Mam-3934
ENSMMUG00000006243.3
F7H5C3
TDRD9
82
LLPS-Mam-0405
ENSMMUG00000012028.3
F7GQI3
TEKT2
83
LLPS-Mam-2069
ENSMMUG00000010955.3
F7GGH8
TNP2
84
LLPS-Mam-0922
ENSMMUG00000020923.3
A0A1D5QQR3
TNPO1
85
LLPS-Mam-3132
ENSMMUG00000020428.3
F6TUK7
TNRC6A
86
LLPS-Mam-1794
ENSMMUG00000013211.3
F7AIG5
TOMM34
87
LLPS-Mam-0785
ENSMMUG00000014487.3
F6QNQ6
TOP3B
88
LLPS-Mam-2014
ENSMMUG00000001185.3
F6TT71
TRA2B
89
LLPS-Mam-3538
ENSMMUG00000004773.3
F6SLJ3
TRPM5
90
LLPS-Mam-4333
ENSMMUG00000008400.3
A0A1D5R513
TTC21B
91
LLPS-Mam-4511
ENSMMUG00000006668.3
F7H3X6
TUBA3C
92
LLPS-Mam-4161
ENSMMUG00000029059.2
F7D7Y7
TUBB3
93
LLPS-Mam-0044
ENSMMUG00000023286.3
F7FFJ3
UPF1
94
LLPS-Mam-3482
ENSMMUG00000013753.3
F6RFQ2
USP9X
95
LLPS-Mam-0343
ENSMMUG00000003193.3
G7N1N6
VIM
96
LLPS-Mam-4309
ENSMMUG00000004101.3
H9EPD6
VPS26A
97
LLPS-Mam-2852
ENSMMUG00000011940.3
I0FFY6
VPS35
98
LLPS-Mam-1539
ENSMMUG00000001376.3
F7D614
YTHDC2