Ictidomys tridecemlineatus      Chromatoid body


※ Chromatoid body introduction

    A single large granule of nuage, presents in post-meiotic spermatids is called the chromatoid body (1). Multiple proteins and some mRNAs have been found to localized to the chromatoid body including mouse VASA homolog , tudor-domain containing 1 (TDRD1), tudor-domain containing 6 (TDRD6), and tudor-domain containing 7 (TDRD7) , transition protein 2 (Tnp2), RANBP9, as a known MVH interactor also localizes to it. Its formation is related to the coalescence of intermitochondrial cement granules. In fact, the formation of the chromatoid body is not required for microRNA biogenesis, but might be important for its action on target mRNAs (1). In mice, the chromatoid body is a structure resembles Gp, TDRD6 plays a role in establishing the body and the localization of piRNA pathway components to this body (2).

Reference
1. Woodruff, J. B., Hyman, A. A., & Boke, E. (2018) Organization and Function of Non-dynamic Biomolecular Condensates. Trends Biochem Sci, 43(2), 81-94. PMID: 30086300
2. Ma, L., Buchold, G. M., Greenbaum, M. P., Roy, A., Burns, K. H., Zhu, H., et al. (2009) GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet, 5(9), e1000635. PMID: 19730684


There are 99 genes.  Reviewed (0 or Unreviewed (99

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Ict-0577
ENSSTOG00000032682.1
A0A287CWI2
2
LLPS-Ict-2326
ENSSTOG00000011255.3
I3NH75
3
LLPS-Ict-4714
ENSSTOG00000033496.1
A0A287DDR0
4
LLPS-Ict-4506
ENSSTOG00000027523.2
I3NFH3
ADAD1
5
LLPS-Ict-4103
ENSSTOG00000008305.3
I3MBF0
ADAD2
6
LLPS-Ict-2189
ENSSTOG00000020460.2
A0A287DAI5
AFAP1L2
7
LLPS-Ict-1492
ENSSTOG00000008113.3
I3MB33
AGO2
8
LLPS-Ict-1970
ENSSTOG00000027547.2
I3MYC0
AKAP4
9
LLPS-Ict-3130
ENSSTOG00000005688.3
I3M6I5
ASZ1
10
LLPS-Ict-4080
ENSSTOG00000006374.3
I3M7T7
CASC3
11
LLPS-Ict-0740
ENSSTOG00000009017.3
I3MCR9
CD74
12
LLPS-Ict-3811
ENSSTOG00000012221.3
I3MIR9
CENPV
13
LLPS-Ict-2249
ENSSTOG00000000173.3
I3LW35
Cnbp
14
LLPS-Ict-1728
ENSSTOG00000030392.1
A0A0U2CKE1
COI
15
LLPS-Ict-0011
ENSSTOG00000004632.3
I3M4L5
DCP1A
16
LLPS-Ict-2514
ENSSTOG00000003977.3
I3M3D3
DDX1
17
LLPS-Ict-2484
ENSSTOG00000003749.3
I3M2W3
DDX25
18
LLPS-Ict-2437
ENSSTOG00000021044.2
I3NFW8
DDX4
19
LLPS-Ict-1065
ENSSTOG00000012526.3
I3MJC2
DDX5
20
LLPS-Ict-1794
ENSSTOG00000016288.3
I3MRA0
DHX9
21
LLPS-Ict-0015
ENSSTOG00000022439.2
I3NGE2
DICER1
22
LLPS-Ict-0505
ENSSTOG00000002888.3
I3M1D5
EDC4
23
LLPS-Ict-1172
ENSSTOG00000024814.2
A0A287DCG9
EIF4A1
24
LLPS-Ict-0766
ENSSTOG00000002664.3
A0A287CVF6
EIF4A3
25
LLPS-Ict-0400
ENSSTOG00000002230.3
I3M004
EIF4E
26
LLPS-Ict-0239
ENSSTOG00000009130.3
I3MCZ4
ELAVL1
27
LLPS-Ict-0700
ENSSTOG00000002618.3
I3M0S5
ENO4
28
LLPS-Ict-2955
ENSSTOG00000023177.2
I3N3L9
Ewsr1
29
LLPS-Ict-1279
ENSSTOG00000008545.2
I3MBT2
FABP9
30
LLPS-Ict-4676
ENSSTOG00000000612.3
I3LX18
FYCO1
31
LLPS-Ict-2901
ENSSTOG00000032740.1
A0A287D705
GPX4
32
LLPS-Ict-2438
ENSSTOG00000020295.1
I3MY06
HIST1H2BA
33
LLPS-Ict-2104
ENSSTOG00000020189.1
I3MVX5
HIST1H3I
34
LLPS-Ict-1119
ENSSTOG00000006202.3
A0A287D861
Hnrnpa2b1
35
LLPS-Ict-1694
ENSSTOG00000025125.2
I3NCR3
HNRNPA3
36
LLPS-Ict-3422
ENSSTOG00000013979.3
A0A287D2H2
HNRNPDL
37
LLPS-Ict-1267
ENSSTOG00000025560.2
I3MYK9
Hnrnpf
38
LLPS-Ict-3818
ENSSTOG00000016376.3
A0A287D1B7
HNRNPH1
39
LLPS-Ict-1249
ENSSTOG00000008112.3
A0A287D670
HNRNPM
40
LLPS-Ict-1576
ENSSTOG00000000153.3
I3LW27
Hnrnpu
41
LLPS-Ict-2784
ENSSTOG00000009643.3
I3MDY9
Hsp90aa1
42
LLPS-Ict-3410
ENSSTOG00000024614.2
I3NCN5
Hsp90ab1
43
LLPS-Ict-3816
ENSSTOG00000029617.1
I3MKH2
Hspa1a
44
LLPS-Ict-1370
ENSSTOG00000008519.3
I3MBS8
IGF2BP3
45
LLPS-Ict-1122
ENSSTOG00000007786.3
A0A287D036
ILF3
46
LLPS-Ict-4648
ENSSTOG00000013735.3
I3MLL0
IP6K1
47
LLPS-Ict-0462
ENSSTOG00000014138.3
I3MMC5
KHDRBS1
48
LLPS-Ict-3831
ENSSTOG00000003961.3
I3M3B7
LAMP1
49
LLPS-Ict-1323
ENSSTOG00000000014.3
I3LVU2
Ldha
50
LLPS-Ict-0419
ENSSTOG00000022024.1
I3N7M0
LOC101966143
51
LLPS-Ict-0308
ENSSTOG00000028945.2
I3N7E8
LOC101971599
52
LLPS-Ict-2926
ENSSTOG00000004693.3
A0A287D6M3
LOC101975061
53
LLPS-Ict-0855
ENSSTOG00000000548.3
I3NBA6
Lyar
54
LLPS-Ict-1337
ENSSTOG00000015434.3
A0A287DAJ3
MAEL
55
LLPS-Ict-1485
ENSSTOG00000029127.2
I3MTI2
ODF1
56
LLPS-Ict-0733
ENSSTOG00000016395.3
I3MZM6
PABPC3
57
LLPS-Ict-1634
ENSSTOG00000026002.2
A0A287CZR4
PCBP1
58
LLPS-Ict-3347
ENSSTOG00000003635.3
I3M2N2
PCBP2
59
LLPS-Ict-0633
ENSSTOG00000005154.3
I3M5L1
PIWIL1
60
LLPS-Ict-0571
ENSSTOG00000016520.3
I3MRQ2
PIWIL2
61
LLPS-Ict-0975
ENSSTOG00000005143.3
I3M5K7
PMPCB
62
LLPS-Ict-4518
ENSSTOG00000002200.3
I3LZY5
PSIP1
63
LLPS-Ict-2789
ENSSTOG00000008308.3
I3MBE3
RANBP9
64
LLPS-Ict-0214
ENSSTOG00000005541.3
I3M683
RANGRF
65
LLPS-Ict-0040
ENSSTOG00000009796.3
I3ME79
RBM14
66
LLPS-Ict-1382
ENSSTOG00000013917.3
I3MLX7
RBM8A
67
LLPS-Ict-4066
ENSSTOG00000013234.3
I3MKL4
RNASE6
68
LLPS-Ict-1299
ENSSTOG00000011328.3
I3M5B9
RPL23A
69
LLPS-Ict-2736
ENSSTOG00000014654.3
A0A287DA37
RPL24
70
LLPS-Ict-0506
ENSSTOG00000026574.2
I3NCA6
RPS14
71
LLPS-Ict-1466
ENSSTOG00000006322.3
I3M7N6
Rps8
72
LLPS-Ict-1774
ENSSTOG00000014364.3
A0A287CYX9
SMG1
73
LLPS-Ict-3143
ENSSTOG00000028127.2
I3NHX0
SMG6
74
LLPS-Ict-1403
ENSSTOG00000003207.3
I3M1U7
SPERT
75
LLPS-Ict-1365
ENSSTOG00000000243.3
A0A287DCN5
Srsf1
76
LLPS-Ict-3112
ENSSTOG00000014280.3
I3N1N9
Srsf3
77
LLPS-Ict-3453
ENSSTOG00000003577.3
I3M2K7
STK31
78
LLPS-Ict-2859
ENSSTOG00000003221.3
I3M1X1
TDRD1
79
LLPS-Ict-0989
ENSSTOG00000026328.2
I3N228
TDRD5
80
LLPS-Ict-3627
ENSSTOG00000028193.2
I3N9T2
TDRD6
81
LLPS-Ict-1867
ENSSTOG00000002628.3
I3NCP3
TDRD7
82
LLPS-Ict-0773
ENSSTOG00000007890.3
I3MAN2
TDRD9
83
LLPS-Ict-2211
ENSSTOG00000010245.3
I3MF40
TEKT2
84
LLPS-Ict-1301
ENSSTOG00000022454.2
I3N4B8
TEKT4
85
LLPS-Ict-3015
ENSSTOG00000023394.2
I3NBQ7
TNRC6A
86
LLPS-Ict-1293
ENSSTOG00000019477.2
I3MXH8
TOMM34
87
LLPS-Ict-0083
ENSSTOG00000019986.2
I3NC26
TOP3B
88
LLPS-Ict-0892
ENSSTOG00000006720.3
I3M8E8
TRA2B
89
LLPS-Ict-1672
ENSSTOG00000021454.2
I3N7F0
TRPM5
90
LLPS-Ict-1998
ENSSTOG00000010989.3
A0A287CTQ3
TTC21B
91
LLPS-Ict-2403
ENSSTOG00000025687.2
I3MXL4
Tubb3
92
LLPS-Ict-0854
ENSSTOG00000006700.3
I3M8C6
UBTD1
93
LLPS-Ict-0914
ENSSTOG00000009196.3
A0A287D9H5
UPF1
94
LLPS-Ict-1522
ENSSTOG00000000797.3
I3LXD2
USP9X
95
LLPS-Ict-1205
ENSSTOG00000022289.2
I3N827
VIM
96
LLPS-Ict-0343
ENSSTOG00000009077.3
A0A287DCM2
VPS26A
97
LLPS-Ict-3389
ENSSTOG00000003772.3
I3M2Y3
VPS35
98
LLPS-Ict-0702
ENSSTOG00000008630.3
I3MBZ2
YBX2
99
LLPS-Ict-2944
ENSSTOG00000013239.3
I3MKM7
YTHDC2