Erinaceus europaeus      Chromatoid body


※ Chromatoid body introduction

    A single large granule of nuage, presents in post-meiotic spermatids is called the chromatoid body (1). Multiple proteins and some mRNAs have been found to localized to the chromatoid body including mouse VASA homolog , tudor-domain containing 1 (TDRD1), tudor-domain containing 6 (TDRD6), and tudor-domain containing 7 (TDRD7) , transition protein 2 (Tnp2), RANBP9, as a known MVH interactor also localizes to it. Its formation is related to the coalescence of intermitochondrial cement granules. In fact, the formation of the chromatoid body is not required for microRNA biogenesis, but might be important for its action on target mRNAs (1). In mice, the chromatoid body is a structure resembles Gp, TDRD6 plays a role in establishing the body and the localization of piRNA pathway components to this body (2).

Reference
1. Woodruff, J. B., Hyman, A. A., & Boke, E. (2018) Organization and Function of Non-dynamic Biomolecular Condensates. Trends Biochem Sci, 43(2), 81-94. PMID: 30086300
2. Ma, L., Buchold, G. M., Greenbaum, M. P., Roy, A., Burns, K. H., Zhu, H., et al. (2009) GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet, 5(9), e1000635. PMID: 19730684


There are 25 genes.  Reviewed (0 or Unreviewed (25

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Ere-0135
ENSEEUG00000000418.1
2
LLPS-Ere-0436
ENSEEUG00000012442.1
3
LLPS-Ere-0555
ENSEEUG00000000925.1
4
LLPS-Ere-0298
ENSEEUG00000014253.1
A0A1S3A8M3
CASC3
5
LLPS-Ere-0617
ENSEEUG00000023932.1
A0A1S2XB46
COX1
6
LLPS-Ere-0433
ENSEEUG00000010847.1
A0A1S3ARR5
DDX25
7
LLPS-Ere-0960
ENSEEUG00000013364.1
A0A1S3WGJ5
HNRNPH1
8
LLPS-Ere-0222
ENSEEUG00000008395.1
A0A1S3A074
IP6K1
9
LLPS-Ere-1069
ENSEEUG00000004634.1
A0A1S2Z9F4
LOC103107131
10
LLPS-Ere-0496
ENSEEUG00000003492.1
A0A1S3W4S7
LOC103108797
11
LLPS-Ere-0563
ENSEEUG00000005920.1
A0A1S2ZTU9
LOC103114676
12
LLPS-Ere-0769
ENSEEUG00000002876.1
A0A1S2ZX81
LOC103116085
13
LLPS-Ere-0359
ENSEEUG00000001161.1
A0A1S3A4A2
LOC103118841
14
LLPS-Ere-0379
ENSEEUG00000002736.1
A0A1S3WQL1
LOC103123927
15
LLPS-Ere-0716
ENSEEUG00000006549.1
A0A1S2ZG93
ODF1
16
LLPS-Ere-0058
ENSEEUG00000002701.1
A0A1S3ABM3
PABPC1
17
LLPS-Ere-0848
ENSEEUG00000002415.1
A0A1S2ZPG0
RANGRF
18
LLPS-Ere-0762
ENSEEUG00000012260.1
A0A1S3ALF2
RNASE6
19
LLPS-Ere-0856
ENSEEUG00000006298.1
A0A1S3WL52
RPL23A
20
LLPS-Ere-0050
ENSEEUG00000010462.1
A0A1S2ZAN3
RPS14
21
LLPS-Ere-1044
ENSEEUG00000009255.1
A0A1S3AML7
SRSF1
22
LLPS-Ere-0600
ENSEEUG00000003317.1
A0A1S3A8A4
TOMM34
23
LLPS-Ere-0206
ENSEEUG00000009822.1
A0A1S2ZID6
TRA2B
24
LLPS-Ere-0632
ENSEEUG00000011797.1
A0A1S3AC50
UBTD1
25
LLPS-Ere-0443
ENSEEUG00000004843.1
A0A1S2ZXR8
VIM