Dipodomys ordii      Chromatoid body


※ Chromatoid body introduction

    A single large granule of nuage, presents in post-meiotic spermatids is called the chromatoid body (1). Multiple proteins and some mRNAs have been found to localized to the chromatoid body including mouse VASA homolog , tudor-domain containing 1 (TDRD1), tudor-domain containing 6 (TDRD6), and tudor-domain containing 7 (TDRD7) , transition protein 2 (Tnp2), RANBP9, as a known MVH interactor also localizes to it. Its formation is related to the coalescence of intermitochondrial cement granules. In fact, the formation of the chromatoid body is not required for microRNA biogenesis, but might be important for its action on target mRNAs (1). In mice, the chromatoid body is a structure resembles Gp, TDRD6 plays a role in establishing the body and the localization of piRNA pathway components to this body (2).

Reference
1. Woodruff, J. B., Hyman, A. A., & Boke, E. (2018) Organization and Function of Non-dynamic Biomolecular Condensates. Trends Biochem Sci, 43(2), 81-94. PMID: 30086300
2. Ma, L., Buchold, G. M., Greenbaum, M. P., Roy, A., Burns, K. H., Zhu, H., et al. (2009) GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet, 5(9), e1000635. PMID: 19730684


There are 93 genes.  Reviewed (0 or Unreviewed (93

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Dio-1050
ENSDORG00000024794.1
2
LLPS-Dio-0826
ENSDORG00000015684.2
A0A1S3FLY6
Adad1
3
LLPS-Dio-3503
ENSDORG00000003555.2
A0A1S3EW36
Adad2
4
LLPS-Dio-2401
ENSDORG00000016621.2
A0A1S3F9U4
Afap1l2
5
LLPS-Dio-1607
ENSDORG00000011242.2
A0A1S3FXC0
Ago2
6
LLPS-Dio-2027
ENSDORG00000014873.2
A0A1S3GIL2
Akap4
7
LLPS-Dio-0463
ENSDORG00000007590.2
A0A1S3FGH9
Asz1
8
LLPS-Dio-1681
ENSDORG00000001514.2
A0A1S3FWK0
Cd74
9
LLPS-Dio-1445
ENSDORG00000027408.1
A0A1S3GFC3
Cenpv
10
LLPS-Dio-1300
ENSDORG00000002919.2
A0A1S3GFZ3
Cnbp
11
LLPS-Dio-1538
ENSDORG00000012477.2
A0A1S3FT11
Ctsb
12
LLPS-Dio-2693
ENSDORG00000012847.2
A0A1S3EZ21
Ddx1
13
LLPS-Dio-2284
ENSDORG00000001822.2
A0A1S3EM63
Ddx25
14
LLPS-Dio-2497
ENSDORG00000012201.2
A0A1S3FD80
Ddx4
15
LLPS-Dio-2971
ENSDORG00000004866.2
A0A1S3GZA6
Ddx5
16
LLPS-Dio-1274
ENSDORG00000006215.2
A0A1S3F437
Dicer1
17
LLPS-Dio-0438
ENSDORG00000010702.2
A0A1S3EWW7
Edc4
18
LLPS-Dio-0422
ENSDORG00000014225.2
A0A1S3EZD2
Eif4a1
19
LLPS-Dio-1309
ENSDORG00000013028.2
A0A1S3GZI7
Eif4a3
20
LLPS-Dio-0641
ENSDORG00000002901.2
A0A1S3GAG3
Eif4e
21
LLPS-Dio-3499
ENSDORG00000009158.2
A0A1S3GK31
Elavl1
22
LLPS-Dio-0690
ENSDORG00000007393.2
A0A1S3FB59
Eno4
23
LLPS-Dio-1039
ENSDORG00000008915.2
A0A1S3F0V8
Ewsr1
24
LLPS-Dio-4161
ENSDORG00000002230.2
A0A1S3EU15
Fabp9
25
LLPS-Dio-3662
ENSDORG00000006539.2
A0A1S3GA29
Fyco1
26
LLPS-Dio-0292
ENSDORG00000002915.2
A0A1S3FQS3
Gpx4
27
LLPS-Dio-0268
ENSDORG00000005482.2
A0A1S3FV39
Hnrnpa2b1
28
LLPS-Dio-0397
ENSDORG00000011155.2
A0A1S3G8F9
Hnrnpa3
29
LLPS-Dio-1415
ENSDORG00000000968.2
A0A1S3FH56
Hnrnpdl
30
LLPS-Dio-1893
ENSDORG00000024298.1
A0A1S3GK59
Hnrnpf
31
LLPS-Dio-0003
ENSDORG00000005453.2
A0A1S3GCH0
Hnrnph1
32
LLPS-Dio-1326
ENSDORG00000008105.2
A0A1S3GLZ7
Hnrnpm
33
LLPS-Dio-3547
ENSDORG00000015491.2
A0A1S3FAG8
Hnrnpu
34
LLPS-Dio-1124
ENSDORG00000005569.2
A0A1S3F3M7
Hsp90aa1
35
LLPS-Dio-0029
ENSDORG00000010981.2
A0A1S3FF49
Hsp90ab1
36
LLPS-Dio-2954
ENSDORG00000030182.1
A0A1S3F7M8
Hspa2
37
LLPS-Dio-2043
ENSDORG00000014185.2
A0A1S3FTQ1
Igf2bp3
38
LLPS-Dio-0911
ENSDORG00000015231.2
A0A1S3GLA3
Ilf3
39
LLPS-Dio-0636
ENSDORG00000007515.2
A0A1S3G479
Ip6k1
40
LLPS-Dio-0572
ENSDORG00000011530.2
A0A1S3FHV2
Khdrbs1
41
LLPS-Dio-1637
ENSDORG00000014590.2
A0A1S3FQI8
Lamp1
42
LLPS-Dio-1193
ENSDORG00000003526.2
A0A1S3FG45
LOC105988070
43
LLPS-Dio-0112
ENSDORG00000002474.2
A0A1S3FIU5
LOC105989192
44
LLPS-Dio-1348
ENSDORG00000029787.1
A0A1S3FTQ6
LOC105991774
45
LLPS-Dio-1205
ENSDORG00000024030.1
A0A1S3G1F1
LOC105993236
46
LLPS-Dio-0242
ENSDORG00000024877.1
A0A1S3GRV1
LOC106000035
47
LLPS-Dio-0701
ENSDORG00000006012.2
A0A1S3FRW9
Lyar
48
LLPS-Dio-2292
ENSDORG00000001149.2
A0A1S3FLM6
Mael
49
LLPS-Dio-3818
ENSDORG00000008364.2
A0A1S3GSM8
Magohb
50
LLPS-Dio-2388
ENSDORG00000012513.2
A0A1S3EMV6
Ncl
51
LLPS-Dio-0364
ENSDORG00000001204.2
A0A1S3FQH4
Nedd1
52
LLPS-Dio-2483
ENSDORG00000003568.2
A0A1S3EU36
Odf1
53
LLPS-Dio-2109
ENSDORG00000013935.2
A0A1S3EU73
Pabpc1
54
LLPS-Dio-2727
ENSDORG00000008216.2
A0A1S3FQ74
Pcbp1
55
LLPS-Dio-0098
ENSDORG00000001384.2
A0A1S3GI79
Pcbp2
56
LLPS-Dio-0369
ENSDORG00000010479.2
A0A1S3FS22
Piwil1
57
LLPS-Dio-3414
ENSDORG00000011177.2
A0A1S3GPF9
Piwil2
58
LLPS-Dio-0508
ENSDORG00000004907.2
A0A1S3FJR2
Psip1
59
LLPS-Dio-0548
ENSDORG00000005280.2
A0A1S3GB00
Ranbp9
60
LLPS-Dio-0050
ENSDORG00000007147.2
A0A1S3EY58
Rangrf
61
LLPS-Dio-0632
ENSDORG00000027340.1
A0A1S3FBZ6
Rbm8a
62
LLPS-Dio-0335
ENSDORG00000012496.2
A0A1S3GPS3
Rpl11
63
LLPS-Dio-1081
ENSDORG00000000974.2
A0A1S3F7H4
Rpl23a
64
LLPS-Dio-2268
ENSDORG00000029678.1
A0A1S3FSU6
Rpl24
65
LLPS-Dio-1460
ENSDORG00000007146.2
A0A1S3FWU7
Rps14
66
LLPS-Dio-0725
ENSDORG00000009287.2
A0A1S3F774
Rps8
67
LLPS-Dio-2581
ENSDORG00000006146.2
A0A1S3ESM9
Smg1
68
LLPS-Dio-3257
ENSDORG00000016614.2
A0A1S3F5R9
Smg6
69
LLPS-Dio-3433
ENSDORG00000026204.1
A0A1S3GWP3
Spert
70
LLPS-Dio-3799
ENSDORG00000015082.2
A0A1S3GYL4
Srsf1
71
LLPS-Dio-1371
ENSDORG00000012283.2
A0A1S3G8C6
Srsf3
72
LLPS-Dio-2838
ENSDORG00000016315.2
A0A1S3FTH6
Stk31
73
LLPS-Dio-1212
ENSDORG00000008714.2
A0A1S3ESV8
Tdrd3
74
LLPS-Dio-3198
ENSDORG00000023519.1
A0A1S3F423
Tdrd5
75
LLPS-Dio-0853
ENSDORG00000013646.2
A0A1S3FQ71
Tdrd7
76
LLPS-Dio-0954
ENSDORG00000015167.2
A0A1S3EXY6
Tdrd9
77
LLPS-Dio-0254
ENSDORG00000001077.2
A0A1S3GLF3
Tekt2
78
LLPS-Dio-2837
ENSDORG00000029374.1
A0A1S3ERM7
Tnrc6a
79
LLPS-Dio-0094
ENSDORG00000001070.2
A0A1S3ERK4
Tomm34
80
LLPS-Dio-0956
ENSDORG00000002012.2
A0A1S3GDY0
Top3b
81
LLPS-Dio-2206
ENSDORG00000026038.1
A0A1S3GN52
Tra2b
82
LLPS-Dio-1549
ENSDORG00000001508.2
A0A1S3FI91
Trpm5
83
LLPS-Dio-3562
ENSDORG00000003317.2
A0A1S3GAR7
Ttc21b
84
LLPS-Dio-2559
ENSDORG00000028053.1
A0A1S3GDP6
Tuba3e
85
LLPS-Dio-1162
ENSDORG00000015304.2
A0A1S3GR06
Tubb3
86
LLPS-Dio-3077
ENSDORG00000029750.1
A0A1S3F8X8
Ubtd1
87
LLPS-Dio-1440
ENSDORG00000009984.2
A0A1S3G6W9
Upf1
88
LLPS-Dio-0116
ENSDORG00000002122.2
A0A1S3G069
Usp9x
89
LLPS-Dio-0945
ENSDORG00000004494.2
A0A1S3F1H2
Vim
90
LLPS-Dio-2242
ENSDORG00000016728.2
A0A1S3F7T4
Vps26a
91
LLPS-Dio-3690
ENSDORG00000002541.2
A0A1S3GU88
Vps35
92
LLPS-Dio-3402
ENSDORG00000010882.2
A0A1S3EVZ0
Ybx2
93
LLPS-Dio-1583
ENSDORG00000007057.2
A0A1S3F4G3
Ythdc2