Cavia porcellus      Chromatoid body


※ Chromatoid body introduction

    A single large granule of nuage, presents in post-meiotic spermatids is called the chromatoid body (1). Multiple proteins and some mRNAs have been found to localized to the chromatoid body including mouse VASA homolog , tudor-domain containing 1 (TDRD1), tudor-domain containing 6 (TDRD6), and tudor-domain containing 7 (TDRD7) , transition protein 2 (Tnp2), RANBP9, as a known MVH interactor also localizes to it. Its formation is related to the coalescence of intermitochondrial cement granules. In fact, the formation of the chromatoid body is not required for microRNA biogenesis, but might be important for its action on target mRNAs (1). In mice, the chromatoid body is a structure resembles Gp, TDRD6 plays a role in establishing the body and the localization of piRNA pathway components to this body (2).

Reference
1. Woodruff, J. B., Hyman, A. A., & Boke, E. (2018) Organization and Function of Non-dynamic Biomolecular Condensates. Trends Biochem Sci, 43(2), 81-94. PMID: 30086300
2. Ma, L., Buchold, G. M., Greenbaum, M. P., Roy, A., Burns, K. H., Zhu, H., et al. (2009) GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet, 5(9), e1000635. PMID: 19730684


There are 100 genes.  Reviewed (0 or Unreviewed (100

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Cap-4668
ENSCPOG00000032476.1
A0A286XQ21
2
LLPS-Cap-4638
ENSCPOG00000014455.4
H0VR27
ADAD1
3
LLPS-Cap-4528
ENSCPOG00000008685.4
H0VCW5
ADAD2
4
LLPS-Cap-1358
ENSCPOG00000004200.4
H0V2L5
AFAP1L2
5
LLPS-Cap-1968
ENSCPOG00000010428.4
A0A286Y3L3
AGO2
6
LLPS-Cap-1797
ENSCPOG00000008990.4
H0VDL4
AKAP4
7
LLPS-Cap-0241
ENSCPOG00000015139.4
H0VSN3
CASC3
8
LLPS-Cap-4060
ENSCPOG00000034371.1
A0A286XK73
CD74
9
LLPS-Cap-2171
ENSCPOG00000037973.1
A0A286XHX4
CENPV
10
LLPS-Cap-1297
ENSCPOG00000032294.1
A0A286XE82
Cnbp
11
LLPS-Cap-1641
ENSCPOG00000017413.2
Q9TEG9
COI
12
LLPS-Cap-1125
ENSCPOG00000009125.4
H0VDW9
CTSB
13
LLPS-Cap-2633
ENSCPOG00000000073.4
H0UT43
DCP1A
14
LLPS-Cap-0377
ENSCPOG00000011456.4
H0VJ77
DDX25
15
LLPS-Cap-2797
ENSCPOG00000004327.4
A0A286XSK5
DDX4
16
LLPS-Cap-0368
ENSCPOG00000007133.4
H0V9E4
DDX5
17
LLPS-Cap-0850
ENSCPOG00000040669.1
A0A286XUL4
DHX9
18
LLPS-Cap-0256
ENSCPOG00000004221.4
H0V2N3
DICER1
19
LLPS-Cap-0772
ENSCPOG00000019484.2
A0A286XGN3
EDC4
20
LLPS-Cap-2850
ENSCPOG00000004067.3
H0V2B3
EEF1A1
21
LLPS-Cap-1261
ENSCPOG00000004900.4
H0V478
Eif4a1
22
LLPS-Cap-0527
ENSCPOG00000006485.4
A0A286XX63
EIF4A3
23
LLPS-Cap-0089
ENSCPOG00000032402.1
A0A286XS61
EIF4E
24
LLPS-Cap-3278
ENSCPOG00000011884.4
H0VK78
ELAVL1
25
LLPS-Cap-4695
ENSCPOG00000010978.4
H0VI57
ENO4
26
LLPS-Cap-4025
ENSCPOG00000009502.4
A0A286XG79
EWSR1
27
LLPS-Cap-1127
ENSCPOG00000008105.4
H0VBK5
FYCO1
28
LLPS-Cap-3307
ENSCPOG00000009750.4
Q07E06
GASZ
29
LLPS-Cap-2257
ENSCPOG00000039362.1
A0A286XUS1
Gpx4
30
LLPS-Cap-0075
ENSCPOG00000036630.1
A0A286XS96
HNRNPA2B1
31
LLPS-Cap-3300
ENSCPOG00000004251.4
H0V2Q9
HNRNPA3
32
LLPS-Cap-0654
ENSCPOG00000015619.4
H0VTS7
Hnrnpdl
33
LLPS-Cap-1480
ENSCPOG00000003678.4
H0W0E9
HNRNPF
34
LLPS-Cap-1670
ENSCPOG00000001485.4
A0A286XJM8
Hnrnph1
35
LLPS-Cap-1365
ENSCPOG00000015182.4
A0A286Y2R3
HNRNPM
36
LLPS-Cap-0569
ENSCPOG00000011887.4
H0VK81
HNRNPU
37
LLPS-Cap-0033
ENSCPOG00000002015.4
H0UXJ8
Hsp90aa1
38
LLPS-Cap-3767
ENSCPOG00000003887.4
H0V1W9
HSP90AB1
39
LLPS-Cap-1477
ENSCPOG00000003486.4
A0A286XLG8
HSPA2
40
LLPS-Cap-1505
ENSCPOG00000015070.4
H0VSH8
IGF2BP3
41
LLPS-Cap-1868
ENSCPOG00000013726.4
H0VPE3
ILF3
42
LLPS-Cap-3738
ENSCPOG00000040339.1
A0A286XIM3
IP6K1
43
LLPS-Cap-3720
ENSCPOG00000024148.2
H0WE19
KHDRBS1
44
LLPS-Cap-2739
ENSCPOG00000021441.2
H0VYG7
LAMP1
45
LLPS-Cap-4306
ENSCPOG00000031440.1
A0A286XIP7
LOC100713875
46
LLPS-Cap-1596
ENSCPOG00000031982.1
A0A286X9R2
LOC100715405
47
LLPS-Cap-3026
ENSCPOG00000000974.4
H0WBX1
LOC100717205
48
LLPS-Cap-0144
ENSCPOG00000009816.4
H0VFG8
LOC100721277
49
LLPS-Cap-4108
ENSCPOG00000038520.1
A0A286Y1U0
LOC100731649
50
LLPS-Cap-0921
ENSCPOG00000039622.1
H0VZ17
LOC100731885
51
LLPS-Cap-4069
ENSCPOG00000040330.1
A0A286XA50
LOC100732882
52
LLPS-Cap-0578
ENSCPOG00000030241.1
H0W865
LOC111756490
53
LLPS-Cap-1792
ENSCPOG00000003923.4
H0V200
Lyar
54
LLPS-Cap-3549
ENSCPOG00000005046.4
H0V4J5
MAEL
55
LLPS-Cap-2381
ENSCPOG00000001034.4
H0UVA7
NCL
56
LLPS-Cap-0806
ENSCPOG00000009631.4
A0A286XQY1
NEDD1
57
LLPS-Cap-3163
ENSCPOG00000012742.4
H0VM47
ODF1
58
LLPS-Cap-0845
ENSCPOG00000012917.4
H0VMJ6
PABPC1
59
LLPS-Cap-2612
ENSCPOG00000013511.3
H0VNW7
PCBP1
60
LLPS-Cap-1532
ENSCPOG00000000967.4
H0UV47
PCBP2
61
LLPS-Cap-0129
ENSCPOG00000004830.4
H0V419
PIWIL1
62
LLPS-Cap-2482
ENSCPOG00000001108.4
H0UVG7
PIWIL2
63
LLPS-Cap-0134
ENSCPOG00000008108.4
H0VBK8
PMPCB
64
LLPS-Cap-4681
ENSCPOG00000005095.4
A0A286X7D3
PSIP1
65
LLPS-Cap-3042
ENSCPOG00000035683.1
W0UUZ1
RAD1
66
LLPS-Cap-2945
ENSCPOG00000011734.4
H0VJV5
RANBP9
67
LLPS-Cap-1743
ENSCPOG00000025429.2
H0VWE1
RANGRF
68
LLPS-Cap-0891
ENSCPOG00000008019.4
H0VBE1
RBM14
69
LLPS-Cap-0896
ENSCPOG00000022453.2
H0W1J3
RBM8A
70
LLPS-Cap-1329
ENSCPOG00000008432.4
A0A286XCE8
RPL11
71
LLPS-Cap-3805
ENSCPOG00000001452.3
H0UW86
Rpl23a
72
LLPS-Cap-3389
ENSCPOG00000034974.1
A0A286XVX7
RPL24
73
LLPS-Cap-0528
ENSCPOG00000024408.2
H0W4J5
RPS14
74
LLPS-Cap-1592
ENSCPOG00000000723.4
H0UUK1
RPS8
75
LLPS-Cap-0198
ENSCPOG00000012606.4
H0VLT8
SMG1
76
LLPS-Cap-1277
ENSCPOG00000014878.4
H0VS20
SMG6
77
LLPS-Cap-3536
ENSCPOG00000036575.1
A0A286XZ38
SPERT
78
LLPS-Cap-2500
ENSCPOG00000032681.1
H0VJX7
Srsf1
79
LLPS-Cap-0992
ENSCPOG00000039027.1
A0A286XIK7
SRSF3
80
LLPS-Cap-2599
ENSCPOG00000032654.1
A0A286XRB6
STK31
81
LLPS-Cap-3911
ENSCPOG00000010437.4
H0VGW3
TDRD3
82
LLPS-Cap-2931
ENSCPOG00000000488.4
H0UU20
TDRD7
83
LLPS-Cap-3407
ENSCPOG00000002760.4
H0UZA7
TDRD9
84
LLPS-Cap-3146
ENSCPOG00000006152.4
H0V752
TEKT2
85
LLPS-Cap-1814
ENSCPOG00000004254.4
H0V2R2
TEKT4
86
LLPS-Cap-3126
ENSCPOG00000003540.4
H0V141
TNPO1
87
LLPS-Cap-2283
ENSCPOG00000036684.1
A0A286XJZ7
TNRC6A
88
LLPS-Cap-0866
ENSCPOG00000030209.1
A0A286X917
TOMM34
89
LLPS-Cap-1371
ENSCPOG00000001812.4
H0UX40
TOP3B
90
LLPS-Cap-0479
ENSCPOG00000006313.4
H0V7I1
TRA2B
91
LLPS-Cap-1873
ENSCPOG00000010253.4
H0VGG6
TRPM5
92
LLPS-Cap-3848
ENSCPOG00000030764.1
A0A286XAH9
TTC21B
93
LLPS-Cap-4559
ENSCPOG00000033582.1
A0A286Y495
UBTD1
94
LLPS-Cap-0593
ENSCPOG00000025463.2
H0VY86
UPF1
95
LLPS-Cap-1934
ENSCPOG00000033622.1
A0A286Y004
USP9X
96
LLPS-Cap-3447
ENSCPOG00000001054.4
H0UVC5
Vim
97
LLPS-Cap-2839
ENSCPOG00000014441.4
A0A286XJZ0
VPS26A
98
LLPS-Cap-3266
ENSCPOG00000003773.4
H0V1N2
VPS35
99
LLPS-Cap-4129
ENSCPOG00000009543.4
H0VEV3
YBX2
100
LLPS-Cap-1628
ENSCPOG00000000272.4
H0UTJ8
YTHDC2