Bos taurus      Chromatoid body


※ Chromatoid body introduction

    A single large granule of nuage, presents in post-meiotic spermatids is called the chromatoid body (1). Multiple proteins and some mRNAs have been found to localized to the chromatoid body including mouse VASA homolog , tudor-domain containing 1 (TDRD1), tudor-domain containing 6 (TDRD6), and tudor-domain containing 7 (TDRD7) , transition protein 2 (Tnp2), RANBP9, as a known MVH interactor also localizes to it. Its formation is related to the coalescence of intermitochondrial cement granules. In fact, the formation of the chromatoid body is not required for microRNA biogenesis, but might be important for its action on target mRNAs (1). In mice, the chromatoid body is a structure resembles Gp, TDRD6 plays a role in establishing the body and the localization of piRNA pathway components to this body (2).

Reference
1. Woodruff, J. B., Hyman, A. A., & Boke, E. (2018) Organization and Function of Non-dynamic Biomolecular Condensates. Trends Biochem Sci, 43(2), 81-94. PMID: 30086300
2. Ma, L., Buchold, G. M., Greenbaum, M. P., Roy, A., Burns, K. H., Zhu, H., et al. (2009) GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet, 5(9), e1000635. PMID: 19730684


There are 104 genes.  Reviewed (14 or Unreviewed (90

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Bot-0144
ENSBTAG00000018423.6
F1MBQ8
DDX5
2
LLPS-Bot-0241
ENSBTAG00000019821.5
Q28141
DHX9
3
LLPS-Bot-0075
ENSBTAG00000014534.6
P68103
EEF1A1
4
LLPS-Bot-0014
ENSBTAG00000016023.4
Q2NL22
EIF4A3
5
LLPS-Bot-0203
ENSBTAG00000040076.4
F1MMA0
ILF3
6
LLPS-Bot-0187
ENSBTAG00000003653.5
Q58DA3
LYAR
7
LLPS-Bot-0229
ENSBTAG00000016174.5
E1B8K6
NCL
8
LLPS-Bot-0221
ENSBTAG00000008985.5
Q5E9A3
PCBP1
9
LLPS-Bot-0134
ENSBTAG00000020757.6
Q3SYT9
PCBP2
10
LLPS-Bot-0060
ENSBTAG00000020905.4
Q3T087
RPL11
11
LLPS-Bot-3128
ENSBTAG00000022278.3
Q24JY1
RPL23A
12
LLPS-Bot-0018
ENSBTAG00000008570.5
Q3T076
RPS14
13
LLPS-Bot-0166
ENSBTAG00000015285.6
Q5E958
RPS8
14
LLPS-Bot-0063
ENSBTAG00000018463.4
P48616
VIM
15
LLPS-Bot-0279
ENSBTAG00000048478.1
P68432
16
LLPS-Bot-0405
ENSBTAG00000040277.2
P62803
17
LLPS-Bot-2364
ENSBTAG00000007606.6
18
LLPS-Bot-3118
ENSBTAG00000016512.6
19
LLPS-Bot-3744
ENSBTAG00000053372.1
20
LLPS-Bot-3502
ENSBTAG00000046191.2
G3N1E5
ADAD1
21
LLPS-Bot-1123
ENSBTAG00000034283.3
F1N4S1
ADAD2
22
LLPS-Bot-2186
ENSBTAG00000004895.6
Q17R10
AFAP1L2
23
LLPS-Bot-1928
ENSBTAG00000001579.6
B0JYP5
AGO2
24
LLPS-Bot-1430
ENSBTAG00000016399.6
F1MYH5
AKAP4
25
LLPS-Bot-3881
ENSBTAG00000000169.4
Q8WMX8
ASZ1
26
LLPS-Bot-0316
ENSBTAG00000006250.5
A5D7H5
CASC3
27
LLPS-Bot-1195
ENSBTAG00000015228.5
Q29630
CD74
28
LLPS-Bot-1751
ENSBTAG00000013274.6
G3N1U1
CENPV
29
LLPS-Bot-0801
ENSBTAG00000012159.6
Q3T0Q6
CNBP
30
LLPS-Bot-2554
ENSBTAG00000012442.6
P07688
CTSB
31
LLPS-Bot-0885
ENSBTAG00000022613.4
P62894
CYCS
32
LLPS-Bot-0487
ENSBTAG00000010863.5
F1N4I7
DCP1A
33
LLPS-Bot-0477
ENSBTAG00000009906.6
Q0IIK5
DDX1
34
LLPS-Bot-3908
ENSBTAG00000004266.6
Q2TBP1
DDX25
35
LLPS-Bot-0847
ENSBTAG00000008871.6
F1MYC6
DDX4
36
LLPS-Bot-0933
ENSBTAG00000012852.6
F1MCQ5
DICER1
37
LLPS-Bot-0854
ENSBTAG00000006417.6
E1BJH1
EDC4
38
LLPS-Bot-2443
ENSBTAG00000000132.3
Q3SZ54
EIF4A1
39
LLPS-Bot-3612
ENSBTAG00000009522.6
Q9N0T5
EIF4E
40
LLPS-Bot-0613
ENSBTAG00000000613.6
Q3ZCE2
ELAVL1
41
LLPS-Bot-4466
ENSBTAG00000004330.6
F6RG16
ENO4
42
LLPS-Bot-0548
ENSBTAG00000017755.6
A8E651
EWSR1
43
LLPS-Bot-4251
ENSBTAG00000039718.2
F1MRS8
FABP9
44
LLPS-Bot-2483
ENSBTAG00000015698.6
G3MZW6
FYCO1
45
LLPS-Bot-1812
ENSBTAG00000053003.1
Q9N2J2
GPX4
46
LLPS-Bot-0622
ENSBTAG00000005726.6
Q2HJ60
HNRNPA2B1
47
LLPS-Bot-3717
ENSBTAG00000021580.6
E1BEG2
HNRNPA3
48
LLPS-Bot-3280
ENSBTAG00000014804.5
F1N2T0
HNRNPDL
49
LLPS-Bot-0969
ENSBTAG00000008853.5
Q5E9J1
HNRNPF
50
LLPS-Bot-1402
ENSBTAG00000009389.6
E1BF20
HNRNPH1
51
LLPS-Bot-1318
ENSBTAG00000021039.6
F1MY44
HNRNPM
52
LLPS-Bot-2099
ENSBTAG00000006270.5
Q76LV2
HSP90AA1
53
LLPS-Bot-1373
ENSBTAG00000000778.5
Q76LV1
HSP90AB1
54
LLPS-Bot-0454
ENSBTAG00000025441.4
Q27975
HSPA1A
55
LLPS-Bot-0433
ENSBTAG00000007807.3
P34933
HSPA2
56
LLPS-Bot-2750
ENSBTAG00000019406.6
F1MPB2
IGF2BP3
57
LLPS-Bot-0503
ENSBTAG00000011595.4
Q0II95
IP6K1
58
LLPS-Bot-3098
ENSBTAG00000012497.4
Q29RQ2
KHDRBS1
59
LLPS-Bot-3194
ENSBTAG00000010242.6
Q05204
LAMP1
60
LLPS-Bot-3462
ENSBTAG00000008683.6
P19858
LDHA
61
LLPS-Bot-2515
ENSBTAG00000016550.6
F1MMI4
MAEL
62
LLPS-Bot-0949
ENSBTAG00000019235.4
Q0VC92
MAGOHB
63
LLPS-Bot-3775
ENSBTAG00000001894.6
Q3B7M6
NEDD1
64
LLPS-Bot-2665
ENSBTAG00000003445.5
Q29438
ODF1
65
LLPS-Bot-0676
ENSBTAG00000046358.2
P61286
PABPC1
66
LLPS-Bot-3050
ENSBTAG00000006468.4
E1BJC4
PIWIL1
67
LLPS-Bot-1072
ENSBTAG00000015835.6
E1B7E6
PIWIL2
68
LLPS-Bot-0534
ENSBTAG00000006876.6
E1B941
PMPCB
69
LLPS-Bot-0558
ENSBTAG00000007872.6
Q8MJG1
PSIP1
70
LLPS-Bot-2174
ENSBTAG00000021556.6
F1MUS0
RANBP9
71
LLPS-Bot-1853
ENSBTAG00000018809.4
F1MW14
RANGRF
72
LLPS-Bot-1754
ENSBTAG00000001225.4
F1MI47
RBM14
73
LLPS-Bot-4179
ENSBTAG00000008792.4
P08904
RNASE6
74
LLPS-Bot-4305
ENSBTAG00000000278.4
E1BFJ4
RNF17
75
LLPS-Bot-2500
ENSBTAG00000013461.4
Q862I1
RPL24
76
LLPS-Bot-3701
ENSBTAG00000020735.5
F1MBL6
SMG1
77
LLPS-Bot-1003
ENSBTAG00000000267.6
E1BFK4
SMG6
78
LLPS-Bot-3876
ENSBTAG00000018580.5
A6QQS3
SPERT
79
LLPS-Bot-1743
ENSBTAG00000014766.4
Q0VCY7
SRSF1
80
LLPS-Bot-2668
ENSBTAG00000040006.3
Q3SZR8
SRSF3
81
LLPS-Bot-4756
ENSBTAG00000010609.6
E1BBF0
STK31
82
LLPS-Bot-2286
ENSBTAG00000006855.5
F1MZE7
TDRD1
83
LLPS-Bot-2409
ENSBTAG00000009308.5
Q2HJG4
TDRD3
84
LLPS-Bot-2340
ENSBTAG00000002407.6
G5E528
TDRD5
85
LLPS-Bot-2207
ENSBTAG00000009978.6
E1BGM7
TDRD6
86
LLPS-Bot-0379
ENSBTAG00000003719.6
A6QLE1
TDRD7
87
LLPS-Bot-3132
ENSBTAG00000020402.6
F1MNA1
TDRD9
88
LLPS-Bot-1702
ENSBTAG00000021714.5
Q2T9Q6
TEKT2
89
LLPS-Bot-0556
ENSBTAG00000012601.4
Q2TA38
TEKT4
90
LLPS-Bot-3907
ENSBTAG00000032884.3
P26377
TNP2
91
LLPS-Bot-1259
ENSBTAG00000007979.6
Q3SYU7
TNPO1
92
LLPS-Bot-1043
ENSBTAG00000017999.6
G3N258
TNRC6A
93
LLPS-Bot-1523
ENSBTAG00000003256.6
E1BGD1
TOMM34
94
LLPS-Bot-1669
ENSBTAG00000001697.6
Q3ZBT6
TRA2B
95
LLPS-Bot-4342
ENSBTAG00000046662.2
G3N377
TRPM5
96
LLPS-Bot-1794
ENSBTAG00000030979.3
F6RP72
TUBA3E
97
LLPS-Bot-2128
ENSBTAG00000023730.3
Q2T9S0
TUBB3
98
LLPS-Bot-2390
ENSBTAG00000012719.4
Q3ZBQ1
UBTD1
99
LLPS-Bot-0804
ENSBTAG00000020922.6
E1BEK9
UPF1
100
LLPS-Bot-2529
ENSBTAG00000006242.6
G5E630
USP9X
101
LLPS-Bot-4787
ENSBTAG00000016882.6
Q0VD53
VPS26A
102
LLPS-Bot-2359
ENSBTAG00000002493.3
Q2HJG5
VPS35
103
LLPS-Bot-1725
ENSBTAG00000009126.5
A5D7M4
YBX2
104
LLPS-Bot-0261
ENSBTAG00000014099.6
F1MNU7
YTHDC2