Bos taurus      Centrosome/Spindle pole body


※ Centrosome/Spindle pole body introduction

    A centrosome is a composite material comprising a pair of 200-nm-long barrel-shaped centrioles surrounded by a dynamic protein mass called the pericentriolar material (PCM), which organizes hundreds to thousands of microtubules that build and position the mitotic spindle in metazoans (1). The seemingly unstructured mitotic PCM provides most of the mass and microtubule nucleation capacity of the centrosome, Mitotic PCM could also be liquid like, the mitotic PCM first assembles through phase separation of SPD-5 molecules around the centrioles. Liquid–liquid phase separation of the SPD-5 scaffold followed by maturation into a gel could explain why mitotic PCM is both spherical and stable (1).

Reference
1. Woodruff, J. B., Hyman, A. A., & Boke, E. (2018) Organization and Function of Non-dynamic Biomolecular Condensates. Trends Biochem Sci, 43(2), 81-94. PMID: 29258725


There are 615 genes.  Reviewed (17 or Unreviewed (598

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Bot-0130
ENSBTAG00000046248.2
Q58CQ2
ARPC1B
2
LLPS-Bot-0239
ENSBTAG00000006246.5
F2Z4J7
CBX5
3
LLPS-Bot-0207
ENSBTAG00000010109.3
P48734
CDK1
4
LLPS-Bot-0241
ENSBTAG00000019821.5
Q28141
DHX9
5
LLPS-Bot-0188
ENSBTAG00000016105.5
Q2HJ65
H2AFY
6
LLPS-Bot-0204
ENSBTAG00000015839.6
G3MY44
MAP4
7
LLPS-Bot-0020
ENSBTAG00000010721.6
A4FUD9
MCM3
8
LLPS-Bot-0195
ENSBTAG00000015172.6
Q2KIZ8
MCM6
9
LLPS-Bot-0163
ENSBTAG00000016347.4
E1BCL3
NPM1
10
LLPS-Bot-0201
ENSBTAG00000000837.5
F1MU08
PARP1
11
LLPS-Bot-0211
ENSBTAG00000012146.6
Q3T0E7
PPP1CA
12
LLPS-Bot-0227
ENSBTAG00000011198.6
P61287
PPP1CC
13
LLPS-Bot-0115
ENSBTAG00000001182.6
Q6Q137
SEPT7
14
LLPS-Bot-0135
ENSBTAG00000013905.6
A7Z065
SMC3
15
LLPS-Bot-0173
ENSBTAG00000019853.6
F1N3W8
SMURF2
16
LLPS-Bot-0225
ENSBTAG00000015612.5
A5PJN6
UTP6
17
LLPS-Bot-0063
ENSBTAG00000018463.4
P48616
VIM
18
LLPS-Bot-0424
ENSBTAG00000048057.2
19
LLPS-Bot-0590
ENSBTAG00000050839.1
20
LLPS-Bot-0929
ENSBTAG00000002248.6
21
LLPS-Bot-0981
ENSBTAG00000010426.6
22
LLPS-Bot-1092
ENSBTAG00000025477.5
23
LLPS-Bot-1288
ENSBTAG00000023169.5
G5E648
24
LLPS-Bot-1292
ENSBTAG00000024874.5
25
LLPS-Bot-1352
ENSBTAG00000050474.1
26
LLPS-Bot-1707
ENSBTAG00000051530.1
27
LLPS-Bot-1800
ENSBTAG00000047582.2
28
LLPS-Bot-1810
ENSBTAG00000014714.6
29
LLPS-Bot-1922
ENSBTAG00000007365.6
30
LLPS-Bot-2313
ENSBTAG00000020963.6
31
LLPS-Bot-2335
ENSBTAG00000045867.2
32
LLPS-Bot-2375
ENSBTAG00000035175.4
33
LLPS-Bot-2635
ENSBTAG00000005917.6
34
LLPS-Bot-2783
ENSBTAG00000006724.4
F1MTZ0
35
LLPS-Bot-2830
ENSBTAG00000005456.6
36
LLPS-Bot-3051
ENSBTAG00000019806.4
37
LLPS-Bot-3525
ENSBTAG00000004694.6
38
LLPS-Bot-3565
ENSBTAG00000038409.3
39
LLPS-Bot-4421
ENSBTAG00000054773.1
40
LLPS-Bot-4587
ENSBTAG00000007093.7
E1BL06
41
LLPS-Bot-4703
ENSBTAG00000051168.1
42
LLPS-Bot-4854
ENSBTAG00000000752.6
43
LLPS-Bot-a249
ENSBTAG00000050313.1
44
LLPS-Bot-3977
ENSBTAG00000021067.6
F2Z4F0
ACTR1A
45
LLPS-Bot-1460
ENSBTAG00000048041.2
A4IFE3
ACTR1B
46
LLPS-Bot-2272
ENSBTAG00000017958.6
E1BFN3
AHI1
47
LLPS-Bot-3976
ENSBTAG00000012724.6
E1BKA3
AJUBA
48
LLPS-Bot-1174
ENSBTAG00000014752.5
F1N388
AKAP11
49
LLPS-Bot-0549
ENSBTAG00000007442.6
F1MXF5
AKAP9
50
LLPS-Bot-2236
ENSBTAG00000017636.6
Q01314
AKT1
51
LLPS-Bot-2258
ENSBTAG00000011172.6
E1B958
ALMS1
52
LLPS-Bot-3978
ENSBTAG00000007395.7
F1MDF3
ALS2
53
LLPS-Bot-2968
ENSBTAG00000027991.5
G3N2V4
ANAPC1
54
LLPS-Bot-1600
ENSBTAG00000013326.4
F2Z4G9
ANAPC10
55
LLPS-Bot-3998
ENSBTAG00000008288.6
E1BLC3
ANKRD26
56
LLPS-Bot-2641
ENSBTAG00000020940.6
P27214
ANXA11
57
LLPS-Bot-3035
ENSBTAG00000018852.6
F1MV51
APC
58
LLPS-Bot-0673
ENSBTAG00000017753.6
Q08E54
APP
59
LLPS-Bot-0797
ENSBTAG00000008585.6
E1BH05
ARHGEF10
60
LLPS-Bot-1328
ENSBTAG00000021343.6
F1MZA2
ARHGEF12
61
LLPS-Bot-4054
ENSBTAG00000000113.6
F1N1F7
ARHGEF2
62
LLPS-Bot-1797
ENSBTAG00000002238.4
Q2TA37
ARL2
63
LLPS-Bot-0589
ENSBTAG00000004318.6
Q2TBW6
ARL3
64
LLPS-Bot-1809
ENSBTAG00000035587.3
G3X811
ARRB2
65
LLPS-Bot-1320
ENSBTAG00000007860.6
F1MM80
ASPM
66
LLPS-Bot-1781
ENSBTAG00000003111.5
E1BEI6
ATM
67
LLPS-Bot-1417
ENSBTAG00000013009.6
Q2TA06
AURKA
68
LLPS-Bot-1611
ENSBTAG00000003261.6
F1MY86
AURKC
69
LLPS-Bot-4422
ENSBTAG00000030162.3
G3X7P3
AXIN2
70
LLPS-Bot-3933
ENSBTAG00000007943.5
A3KMV9
AZIN1
71
LLPS-Bot-0282
ENSBTAG00000033690.4
F1MAV4
BARD1
72
LLPS-Bot-3025
ENSBTAG00000020147.5
E1BN34
BBS1
73
LLPS-Bot-1982
ENSBTAG00000007614.4
Q1JQ97
BBS4
74
LLPS-Bot-3843
ENSBTAG00000010736.5
A6QLF9
BBS5
75
LLPS-Bot-3378
ENSBTAG00000004945.6
F1MB52
BBS7
76
LLPS-Bot-2906
ENSBTAG00000005250.6
P21809
BGN
77
LLPS-Bot-3134
ENSBTAG00000013573.3
Q6J1J1
BIRC5
78
LLPS-Bot-1016
ENSBTAG00000010739.6
F1N5K4
BLOC1S2
79
LLPS-Bot-4567
ENSBTAG00000003669.6
F1MUR4
BNC2
80
LLPS-Bot-0958
ENSBTAG00000013079.5
B2CML0
BORIS
81
LLPS-Bot-4817
ENSBTAG00000021761.6
F1MDL4
BRAF
82
LLPS-Bot-2159
ENSBTAG00000022520.5
Q864U1
BRCA1
83
LLPS-Bot-2710
ENSBTAG00000000988.6
E1B8X8
BRCA2
84
LLPS-Bot-0880
ENSBTAG00000015226.6
F1MXK4
BRSK1
85
LLPS-Bot-4119
ENSBTAG00000006167.6
F1MRM6
BTBD8
86
LLPS-Bot-2837
ENSBTAG00000034222.4
F1MMV6
CAB39L
87
LLPS-Bot-4177
ENSBTAG00000031483.3
P62157
CALM
88
LLPS-Bot-3245
ENSBTAG00000012667.6
F1MVF1
CAMK2G
89
LLPS-Bot-2761
ENSBTAG00000005432.3
Q865V6
CAPG
90
LLPS-Bot-4576
ENSBTAG00000018159.6
E1BJT6
CASP2
91
LLPS-Bot-2452
ENSBTAG00000015874.6
F1MB04
CASP3
92
LLPS-Bot-3508
ENSBTAG00000006588.4
Q8MJK1
CBY1
93
LLPS-Bot-4442
ENSBTAG00000017157.5
E1BHP1
CCDC110
94
LLPS-Bot-2410
ENSBTAG00000004604.4
Q2TBV6
CCDC124
95
LLPS-Bot-3467
ENSBTAG00000027875.4
F1MHQ9
CCDC141
96
LLPS-Bot-1263
ENSBTAG00000021346.5
F1MZA1
CCDC34
97
LLPS-Bot-2849
ENSBTAG00000000049.6
A6QPV2
CCDC77
98
LLPS-Bot-0964
ENSBTAG00000017469.6
F1MAY4
CCDC88A
99
LLPS-Bot-3820
ENSBTAG00000014434.5
F1N2Z6
CCHCR1
100
LLPS-Bot-0811
ENSBTAG00000007284.6
F1MVR8
CCNA1
101
LLPS-Bot-0520
ENSBTAG00000004943.5
G8JKW1
CCNA2
102
LLPS-Bot-0323
ENSBTAG00000014239.6
Q1LZG6
CCNB1
103
LLPS-Bot-2110
ENSBTAG00000004906.6
Q5E9K7
CCNE2
104
LLPS-Bot-2551
ENSBTAG00000024884.5
A5PK16
CCNF
105
LLPS-Bot-2844
ENSBTAG00000021768.6
E1BIN6
CCNG2
106
LLPS-Bot-4390
ENSBTAG00000003960.5
E1BGQ5
CCP110
107
LLPS-Bot-2095
ENSBTAG00000000079.6
E1BCI5
CCSAP
108
LLPS-Bot-2549
ENSBTAG00000031439.4
G3MYT6
CDC14A
109
LLPS-Bot-2184
ENSBTAG00000011589.6
E1BMN3
CDC14B
110
LLPS-Bot-3036
ENSBTAG00000019971.6
E1BPM5
CDC16
111
LLPS-Bot-3451
ENSBTAG00000009819.6
F1MRW5
CDC20
112
LLPS-Bot-3842
ENSBTAG00000009586.6
A7MBD1
CDC25A
113
LLPS-Bot-3869
ENSBTAG00000008436.6
E1BL76
CDC25B
114
LLPS-Bot-0816
ENSBTAG00000005293.6
A5D7P0
CDC25C
115
LLPS-Bot-4246
ENSBTAG00000002726.5
A7Z061
CDC27
116
LLPS-Bot-0909
ENSBTAG00000001700.6
Q2KJ93
CDC42
117
LLPS-Bot-2318
ENSBTAG00000031242.4
G3X7R6
CDCA4
118
LLPS-Bot-3789
ENSBTAG00000034373.4
Q3B7N0
CDH13
119
LLPS-Bot-3522
ENSBTAG00000010737.5
F1N5K1
CDK11B
120
LLPS-Bot-2036
ENSBTAG00000004021.3
Q5E9Y0
CDK2
121
LLPS-Bot-0694
ENSBTAG00000006532.6
F1MGF7
CDK5RAP2
122
LLPS-Bot-3123
ENSBTAG00000014202.5
F1MM23
CDK5RAP3
123
LLPS-Bot-2746
ENSBTAG00000008353.5
A5PKM2
CDKN1A
124
LLPS-Bot-2606
ENSBTAG00000019496.5
Q32PC4
CDKN3
125
LLPS-Bot-1085
ENSBTAG00000024449.5
F1N1F8
CENPF
126
LLPS-Bot-2854
ENSBTAG00000017048.4
E1BL95
CENPJ
127
LLPS-Bot-2915
ENSBTAG00000020014.5
E1BND2
CEP104
128
LLPS-Bot-2809
ENSBTAG00000033680.5
F1MMT4
CEP112
129
LLPS-Bot-2024
ENSBTAG00000013184.6
A0JN62
CEP120
130
LLPS-Bot-1150
ENSBTAG00000000875.6
E1BH47
CEP131
131
LLPS-Bot-1642
ENSBTAG00000009471.6
F1ME99
CEP135
132
LLPS-Bot-4247
ENSBTAG00000011661.6
E1BCR3
CEP152
133
LLPS-Bot-0630
ENSBTAG00000003384.5
F1MZ01
CEP162
134
LLPS-Bot-4095
ENSBTAG00000014137.6
F1MNI1
CEP164
135
LLPS-Bot-3733
ENSBTAG00000007566.6
E1BGI2
CEP170
136
LLPS-Bot-3566
ENSBTAG00000013192.5
A6H7C9
CEP19
137
LLPS-Bot-4090
ENSBTAG00000013380.5
F1MAX3
CEP192
138
LLPS-Bot-3866
ENSBTAG00000006021.5
E1BKP6
CEP250
139
LLPS-Bot-2598
ENSBTAG00000018745.6
Q9TU23
CEP290
140
LLPS-Bot-3042
ENSBTAG00000001902.6
F1N4A0
CEP295
141
LLPS-Bot-4361
ENSBTAG00000008082.6
E1BC48
CEP350
142
LLPS-Bot-2846
ENSBTAG00000007413.6
F1MUG2
CEP41
143
LLPS-Bot-4697
ENSBTAG00000020055.5
F1N402
CEP44
144
LLPS-Bot-1961
ENSBTAG00000005129.6
E1B8M0
CEP55
145
LLPS-Bot-1688
ENSBTAG00000016547.6
F1MM87
CEP57
146
LLPS-Bot-1765
ENSBTAG00000007014.6
E1BDP9
CEP63
147
LLPS-Bot-3562
ENSBTAG00000016717.5
E1BPP3
CEP68
148
LLPS-Bot-3826
ENSBTAG00000018538.6
F1ME79
CEP70
149
LLPS-Bot-1482
ENSBTAG00000011405.6
E1BPC1
CEP72
150
LLPS-Bot-3223
ENSBTAG00000010547.6
E1B8D7
CEP76
151
LLPS-Bot-3136
ENSBTAG00000004484.6
E1B7N9
CEP83
152
LLPS-Bot-3137
ENSBTAG00000012929.5
F1MH68
CEP85L
153
LLPS-Bot-4848
ENSBTAG00000004864.6
F1MIX9
CEP89
154
LLPS-Bot-1176
ENSBTAG00000014002.7
F1MLU4
CEP95
155
LLPS-Bot-2156
ENSBTAG00000012320.3
Q32LE3
CETN1
156
LLPS-Bot-2722
ENSBTAG00000007844.4
Q2TBN3
CETN2
157
LLPS-Bot-0413
ENSBTAG00000014373.4
F1N547
CETN3
158
LLPS-Bot-2031
ENSBTAG00000016147.6
Q32LH2
CETN4
159
LLPS-Bot-2858
ENSBTAG00000017582.5
A5D7V1
CHEK1
160
LLPS-Bot-2579
ENSBTAG00000004956.4
Q58DJ9
CHEK2
161
LLPS-Bot-0654
ENSBTAG00000007591.6
Q95KV1
CHUK
162
LLPS-Bot-1531
ENSBTAG00000021275.4
Q17QE5
CIB1
163
LLPS-Bot-4483
ENSBTAG00000021162.6
F1MBA0
CKAP2
164
LLPS-Bot-1804
ENSBTAG00000004448.6
E1B7K5
CKAP5
165
LLPS-Bot-1356
ENSBTAG00000019781.6
G3N2Y5
CLASP1
166
LLPS-Bot-4825
ENSBTAG00000009470.6
Q9XSA7
CLIC4
167
LLPS-Bot-2509
ENSBTAG00000016779.6
E3W9A2
CLIP1
168
LLPS-Bot-2464
ENSBTAG00000001847.7
E1BMK9
CNTLN
169
LLPS-Bot-2528
ENSBTAG00000011417.7
E1BJH3
CNTRL
170
LLPS-Bot-4746
ENSBTAG00000047756.2
G3N091
CNTROB
171
LLPS-Bot-3941
ENSBTAG00000019516.6
A7MBI7
COMT
172
LLPS-Bot-2932
ENSBTAG00000013425.6
G3X736
COPS2
173
LLPS-Bot-1121
ENSBTAG00000018973.4
A6H7B5
COPS3
174
LLPS-Bot-1795
ENSBTAG00000006950.5
Q3SZA0
COPS4
175
LLPS-Bot-3297
ENSBTAG00000002784.6
F1MBP8
COPS5
176
LLPS-Bot-3138
ENSBTAG00000002871.6
F1MG10
COPS6
177
LLPS-Bot-1788
ENSBTAG00000011111.6
F6QE33
COPS7A
178
LLPS-Bot-4256
ENSBTAG00000005207.4
Q2KI56
COPS7B
179
LLPS-Bot-1937
ENSBTAG00000005854.5
A4FV74
COPS8
180
LLPS-Bot-3195
ENSBTAG00000012909.6
P62964
CRABP1
181
LLPS-Bot-1458
ENSBTAG00000004292.6
E1BER6
CRMP1
182
LLPS-Bot-0614
ENSBTAG00000003822.6
E1BBS9
CROCC
183
LLPS-Bot-2820
ENSBTAG00000000434.6
P02510
CRYAB
184
LLPS-Bot-3303
ENSBTAG00000005326.6
P67827
CSNK1A1
185
LLPS-Bot-0902
ENSBTAG00000019986.5
P35508
CSNK1D
186
LLPS-Bot-0550
ENSBTAG00000012341.6
P68399
CSNK2A1
187
LLPS-Bot-1166
ENSBTAG00000013784.5
P20427
CSNK2A2
188
LLPS-Bot-0904
ENSBTAG00000014689.6
F1N192
CSPP1
189
LLPS-Bot-0859
ENSBTAG00000008480.6
F1MYP4
CTBP1
190
LLPS-Bot-1286
ENSBTAG00000013757.6
Q08DH9
CTCF
191
LLPS-Bot-1111
ENSBTAG00000016420.5
Q0VCX4
CTNNB1
192
LLPS-Bot-3651
ENSBTAG00000002411.6
E1BQ11
CTNND1
193
LLPS-Bot-1238
ENSBTAG00000006071.5
Q1RMR3
CTTN
194
LLPS-Bot-1745
ENSBTAG00000008736.6
F1MYD0
CUL1
195
LLPS-Bot-3802
ENSBTAG00000020417.4
A7MB69
DAPK3
196
LLPS-Bot-1235
ENSBTAG00000004358.6
F1MEQ5
DARS2
197
LLPS-Bot-4290
ENSBTAG00000021573.6
Q3MHH0
DCAF12
198
LLPS-Bot-0710
ENSBTAG00000004887.6
F1MIC9
DCTN1
199
LLPS-Bot-2857
ENSBTAG00000010624.5
Q3ZCF0
DCTN2
200
LLPS-Bot-1697
ENSBTAG00000018883.6
Q0P5A1
DCTN3
201
LLPS-Bot-3617
ENSBTAG00000006410.6
Q58D67
DCTN5
202
LLPS-Bot-3330
ENSBTAG00000019591.6
E1BBU3
DCX
203
LLPS-Bot-1449
ENSBTAG00000012443.7
E1BMN2
DIAPH3
204
LLPS-Bot-0709
ENSBTAG00000008665.5
F1MD63
DIXDC1
205
LLPS-Bot-2104
ENSBTAG00000031388.5
E1BPX5
DNAAF4
206
LLPS-Bot-1335
ENSBTAG00000016874.4
Q3MI00
DNAJB1
207
LLPS-Bot-2541
ENSBTAG00000013362.6
A6H7I5
DNM2
208
LLPS-Bot-3979
ENSBTAG00000018142.6
E1BJV8
DTL
209
LLPS-Bot-4631
ENSBTAG00000004776.5
A3KN00
DUSP23
210
LLPS-Bot-0388
ENSBTAG00000016598.5
E1BDX8
DYNC1H1
211
LLPS-Bot-0767
ENSBTAG00000027134.4
Q29RQ3
DYNC1I1
212
LLPS-Bot-3592
ENSBTAG00000002646.6
F1N7H7
DYNC1I2
213
LLPS-Bot-2027
ENSBTAG00000014700.6
Q2KII9
DYNC1LI1
214
LLPS-Bot-0940
ENSBTAG00000000458.5
F1MBQ0
DYNC1LI2
215
LLPS-Bot-2749
ENSBTAG00000024605.5
P61285
DYNLL1
216
LLPS-Bot-1078
ENSBTAG00000025313.3
Q3MHR3
DYNLL2
217
LLPS-Bot-2628
ENSBTAG00000006134.5
Q3T140
DYNLRB1
218
LLPS-Bot-3861
ENSBTAG00000017752.4
Q32P85
DYNLRB2
219
LLPS-Bot-1626
ENSBTAG00000006712.6
F1MGK9
ECPAS
220
LLPS-Bot-3337
ENSBTAG00000017810.6
E1BKH1
EFHC1
221
LLPS-Bot-2842
ENSBTAG00000002528.7
E1B7R4
EIF3A
222
LLPS-Bot-2097
ENSBTAG00000027654.5
Q0P5A7
EIF4EBP1
223
LLPS-Bot-0907
ENSBTAG00000011274.6
A6QR19
ENO2
224
LLPS-Bot-2733
ENSBTAG00000006667.6
Q9N179
EPB41
225
LLPS-Bot-1849
ENSBTAG00000015181.6
A5PK37
EPM2A
226
LLPS-Bot-3770
ENSBTAG00000008934.5
F1MW01
ESPL1
227
LLPS-Bot-2394
ENSBTAG00000006515.6
E1BHC8
ESPN
228
LLPS-Bot-3436
ENSBTAG00000011363.6
F1MRM9
EVI5
229
LLPS-Bot-0548
ENSBTAG00000017755.6
A8E651
EWSR1
230
LLPS-Bot-1974
ENSBTAG00000008638.5
Q58DG5
FAM110A
231
LLPS-Bot-1034
ENSBTAG00000050550.1
Q2KJ38
FAM110B
232
LLPS-Bot-4487
ENSBTAG00000009290.5
E1BHZ3
FAM161A
233
LLPS-Bot-0870
ENSBTAG00000001906.6
E1B6X8
FANCA
234
LLPS-Bot-4693
ENSBTAG00000009124.5
Q5BIR8
FEZ1
235
LLPS-Bot-2287
ENSBTAG00000015457.6
A4IFL5
FGFR1
236
LLPS-Bot-2117
ENSBTAG00000014495.6
Q2YDD1
FGFR1OP
237
LLPS-Bot-3484
ENSBTAG00000008704.6
F1MZY6
FIGN
238
LLPS-Bot-2639
ENSBTAG00000001500.5
F1MNE5
FIGNL1
239
LLPS-Bot-2853
ENSBTAG00000025443.5
F1MS52
FNIP1
240
LLPS-Bot-2643
ENSBTAG00000032640.4
A6QLQ4
FOPNL
241
LLPS-Bot-4171
ENSBTAG00000005999.5
Q05B84
FSD1
242
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