Homo sapiens      Balbiani body


※ Balbiani body introduction

    The Balbiani body is a structure conserved from insects to humans that appears as a large granule, similar to a mRNP granule composed of mRNA and proteins (1). It has amyloid-like properties and can connect cortical actin (1). In addition, Wilsch-Bräuninger et al. suggest that the sponge bodies, a subcellular structure in nurse cells and oocytes, are homologous to the mitochondrial cloud in Xenopus oocytes (2).

Reference
1. Escobar-Aguirre, M., Zhang, H., Jamieson-Lucy, A., & Mullins, M. C. (2017) Microtubule-actin crosslinking factor 1 (Macf1) domain function in Balbiani body dissociation and nuclear positioning. PLoS Genet, 13(9), e1006983. PMID:28880872
2. Wilsch-Bräuninger, M.,Wilsch-Bräuninger, M., Nüsslein-Volhard C. (1997) A sponge-like structure involved in the association and transport of maternal products during Drosophila oogenesis. J Cell Biol, 139(3), 817-29. PMID:9348297


There are 7 genes.  Reviewed (5 or Unreviewed (2

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Hos-1950
ENSG00000071626.16
Q96EP5
DAZAP1
2
LLPS-Hos-1988
ENSG00000127603.25
Q9UPN3
MACF1
3
LLPS-Hos-2582
ENSG00000125207.7
Q96J94
PIWIL1
4
LLPS-Hos-0792
ENSG00000157110.15
Q93062
RBPMS
5
LLPS-Hos-1156
ENSG00000166831.8
Q6ZRY4
RBPMS2
6
LLPS-Hos-3167
ENSG00000204435.13
P67870
CSNK2B
7
LLPS-Hos-2996
ENSG00000180113.15
O60522
TDRD6